Quantitative aspects of the release of leukocyte pyrogen from rabbit blood incubated with endotoxin.

The Journal of experimental medicine ·Vol. 126 ·No. 5 ·1967-11-01 ·Pages 763-81

Murphy PA

Abstract

This paper describes the relations between the endotoxin concentration and leukocyte pyrogen yield when endotoxin is incubated with whole rabbit blood for 24 hr. The results provide strong evidence for the view that leukocyte pyrogen is not modified endotoxin, and also show that the simplified assay method described in the previous paper works reasonably well.

MeSH Terms

Animals Biological Assay Endotoxins/pharmacology In Vitro Techniques Leukocytes/metabolism Proteus Pyrogens/blood Rabbits

Chemicals

Endotoxins Pyrogens

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Murphy P A

References (1)

1 references, click to expand

An assay method for leukocyte pyrogen.
J Exp Med. 1967 Nov 1;126(5):745-61 PMID: 4863132

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.126.5.763

Published

1967-11-01

Pages

763-81

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2138400

Subset

External Links

PubMed source DOI: 10.1084/jem.126.5.763 PMC Full Text View journal details

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Quantitative aspects of the release of leukocyte pyrogen from rabbit blood incubated with endotoxin.

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