Serological comparison of spherules and arthrospores of Coccidioides immitis.

Journal of bacteriology ·Vol. 94 ·No. 5 ·1967-11-00 ·Pages 1400-5

Landay ME, Wheat RW, Conant NF, Lowe EP

Abstract

Spherule and arthrospore cellular preparations were sonic-treated and separated into their respective supernatant and sediment components. Complement-fixation tests with antispherule and antiarthrospore pooled rabbit sera revealed that the soluble antigens exhibited more serological activity than the sediment preparations. After autoclaving, an arthrospore cellular antigen exhibited increased activity with either antisera, whereas autoclaved spherules exhibited increased activity only with antispherule serum. Complement-fixation tests with coccicioidin and spherule culture supernatant preparations revealed quantitative or qualitative differences in antigenic determinants between these two morphological phases of Coccidioides immitis.

MeSH Terms

Antigen-Antibody Reactions Antigens Blastomyces Candida Coccidioides/immunology Complement Fixation Tests Histoplasma Hot Temperature Immune Sera Spores Toxins, Biological

Chemicals

Antigens Immune Sera Toxins, Biological

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Landay M E

Wheat R W

Conant N F

Lowe E P

References (15)

15 references, click to expand

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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.94.5.1400-1405.1967

Published

1967-11-00

Pages

1400-5

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC276838

Subset

External Links

PubMed source DOI: 10.1128/jb.94.5.1400-1405.1967 PMC Full Text View journal details

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Serological comparison of spherules and arthrospores of Coccidioides immitis.

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