Regulation of triglyceride synthesis in the parturient guinea-pig mammary gland.

The Biochemical journal ·Vol. 105 ·No. 1 ·1967-10-00 ·Pages 225-31

Kuhn NJ

Abstract

1. The specific activity of the enzyme palmitoyl-CoA-l-glycerol 3-phosphate palmitoyltransferase (EC 2.3.1.15) in the mammary tissue of guinea pigs has been shown to increase 37-fold at parturition. 2. Increases also occur in tissue concentrations of glycerol 3-phosphate, CoA and free fatty acid, but not in that of acid-insoluble CoA. 3. The isolation and fatty acid composition of plasma triglyceride and of mammary-tissue free fatty acid, diglyceride and triglyceride are described. 4. The findings are discussed in relation to the regulation of milk fat synthesis.

MeSH Terms

Acyltransferases/metabolism Animals Chromatography, Gas Coenzyme A/metabolism Fatty Acids/blood,metabolism Fatty Acids, Nonesterified/metabolism Female Glycerides/metabolism Glycerophosphates/metabolism Guinea Pigs Lactation Lipids/biosynthesis Mammary Glands, Animal/metabolism Milk Postpartum Period Pregnancy Pregnancy, Animal Triglycerides/biosynthesis,blood

Chemicals

Fatty Acids Fatty Acids, Nonesterified Glycerides Glycerophosphates Lipids Triglycerides Acyltransferases Coenzyme A

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Kuhn N J

References (28)

28 references, click to expand

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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj1050225

Published

1967-10-00

Pages

225-31

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1198293

Subset

External Links

PubMed source DOI: 10.1042/bj1050225 PMC Full Text View journal details

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Regulation of triglyceride synthesis in the parturient guinea-pig mammary gland.

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