Home LiteratureArticle Details

PMID: 604249 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Improved technique for electrophoresis of human galactose-1-p uridyl transferase (EC 2.7.7.12).

Human genetics ·Vol. 40 ·No. 1 ·1977-12-29 ·Pages 93-7

Sparkes MC, Crist M, Sparkes RS

Abstract

A newly developed electrophoretic technique for human galactose-1-phosphate uridyl transferase confirms the multiple band patterns for the Duarte and Los Angeles variants. This represents the first confirmation for the Los Angeles variant. The observed frequencies of N, D, and LA types are similar to earlier reports for these variants.

MeSH Terms

Electrophoresis, Starch Gel/methods Galactosemias/enzymology Humans Isoenzymes Nucleotidyltransferases/isolation & purification UTP-Hexose-1-Phosphate Uridylyltransferase/isolation & purification

Chemicals

Isoenzymes Nucleotidyltransferases UTP-Hexose-1-Phosphate Uridylyltransferase

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Sparkes M C

Crist M

Sparkes R S

References (8)

8 references, click to expand

[Investigations on the polymorphism of galactose-1-phosphate-uridyl-transferase by means of agarose gel electrophoresis].
Humangenetik. 1974;24(3):227-30 PMID: 4442869
Electrophoretic variation of galactose-1-phosphate uridyltransferase.
Science. 1966 Dec 2;154(3753):1179-80 PMID: 5921375
The genetics of galactose-1-phosphate uridyl transferase deficiency.
J Lab Clin Med. 1966 Oct;68(4):646-58 PMID: 5923253
A new variant of galactose-1-phosphate uridyltransferase in man: the Los Angeles variant.
Ann Hum Genet. 1973 Jul;37(1):1-8 PMID: 4759900
Population genetics of red cell galactose-1-phosphate-uridyl-transferase (EC:2.7.7.12).
Humangenetik. 1972;17(1):79-80 PMID: 4647724
Galactose-1-phosphate uridyl transferase in fibroblasts: isozymes in normal and variant states.
Ann Hum Genet. 1975 Oct;39(2):147-50 PMID: 1052762
Purification of normal and inactive galactosemic galactose-1-phosphate uridylyltransferase from human red cells.
J Biol Chem. 1976 Feb 25;251(4):1057-63 PMID: 814122
A method for galactose-1-phosphate uridyltransferase assay and the separation of its isozymes by DEAE-cellulose column chromatography.
Clin Chim Acta. 1976 Aug 2;70(3):371-7 PMID: 947629

Article Info

Journal

Human genetics

Abbr.

Hum Genet

ISSN

0340-6717

DOI

10.1007/BF00280835

Published

1977-12-29

Pages

93-7

Language

English

Region

Germany

NLM ID

7613873

Subset

External Links

PubMed source DOI: 10.1007/BF00280835 View journal details

Analysis Services

Improved technique for electrophoresis of human galactose-1-p uridyl transferase (EC 2.7.7.12).

Contact

WeChat Official Account