Effect of diabetes on the concentration of amino acids in plasma and heart muscle of rats.

The Biochemical journal ·Vol. 99 ·No. 1 ·1966-04-00 ·Pages 173-8

Scharff R, Wool IG

Abstract

1. The effect of three types of diabetes (alloxan, partial pancreatectomy and anti-insulin serum) on the concentrations of individual amino acids in the plasma and heart muscle of rats was studied. 2. Insulin deficiency produced complex alterations in the concentrations of amino acids in plasma and heart muscle; the concentrations of some (alanine, valine, leucine and isoleucine) increased, others decreased and a small number were unchanged. The complexity of the results may in part be attributed to the diverse hormonal and metabolic changes that accompany diabetes.

MeSH Terms

Amino Acids/blood,metabolism Animals Carbon Isotopes Chromatography Diabetes Mellitus/metabolism Diabetes Mellitus, Experimental/metabolism Immune Sera Insulin Antibodies Male Myocardium/metabolism Pancreatectomy Rats

Chemicals

Amino Acids Carbon Isotopes Immune Sera Insulin Antibodies

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Scharff R

Wool I G

References (15)

15 references, click to expand

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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj0990173

Published

1966-04-00

Pages

173-8

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1264973

Subset

External Links

PubMed source DOI: 10.1042/bj0990173 PMC Full Text View journal details

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Effect of diabetes on the concentration of amino acids in plasma and heart muscle of rats.

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