Repair of ionizing radiation induced DNA damage in human lymphocytes.

Nucleic acids research ·Vol. 4 ·No. 11 ·1977-11-00 ·Pages 4015-22

Lavin MF, Kidson C

Abstract

Phytohemagglutinin stimulated human lymphocytes exhibit a 20 fold increase in DNA repair synthesis following ionizing radiation damage compared to the level of repair in unstimulated cells. The peak of repair synthesis coincides with that for DNA replication. Stimulated lymphocytes provide a relatively simple assay for ionizing radiation repair defects.

MeSH Terms

DNA/radiation effects DNA Repair Dose-Response Relationship, Radiation Humans Lectins/pharmacology Lymphocyte Activation/radiation effects Lymphocytes/metabolism,radiation effects

Chemicals

Lectins DNA

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Lavin M F

Kidson C

References (29)

29 references, click to expand

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/4.11.4015

Published

1977-11-00

Pages

4015-22

Language

English

Region

England

NLM ID

0411011

PMCID

PMC343218

Subset

External Links

PubMed source DOI: 10.1093/nar/4.11.4015 PMC Full Text View journal details

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Repair of ionizing radiation induced DNA damage in human lymphocytes.

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