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PMID: 593339 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Spatial configuration of mRNA 5'-terminus.

Nature ·Vol. 270 ·No. 5634 ·1977-11-17 ·Pages 223-7

Kim CH, Sarma RH

Abstract

Nuclear magnetic resonance investigation has revealed that the 5'-terminus m7G5'ppp5'Am of mRNA displays a spatial configuration in which the bases form stacked arrays. Details of the conformation as derived from coupling constants, shift trends and ring current considerations are discussed.

MeSH Terms
Base Sequence Guanine Nucleotides Magnetic Resonance Spectroscopy Models, Molecular Nucleic Acid Conformation Oligonucleotides RNA, Messenger Ribonucleosides Temperature
Chemicals
Guanine Nucleotides Oligonucleotides RNA, Messenger Ribonucleosides
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kim C H
Sarma R H
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/270223a0
Published
1977-11-17
Pages
223-7
Language
English
Region
England
NLM ID
0410462
Subset
IM
External Links
PubMed source DOI: 10.1038/270223a0 View journal details
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