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PMID: 5926740 Published · ppublish English Journal Article

Production in FL cells of infectious and potentially infectious reovirus.

Journal of bacteriology ·Vol. 92 ·No. 4 ·1966-10-00 ·Pages 1036-40

Spendlove RS, Lennette EH, Knight CO, Chin JN

Abstract

Spendlove, Rex S. (California State Department of Public Health, Berkeley), Edwin H. Lennette, Charles O. Knight, and Jean N. Chin. Production in FL cells of infectious and potentially infectious reovirus. J. Bacteriol. 92:1036-1040. 1966.-A comparative study was made of the development in, and release from, FL cells of infectious and potentially infectious (chymotrypsin-activatable) reovirus (Lang strain). The latent period was shorter, the rate of synthesis was more rapid, and the total yield was more than 10-fold greater in potentially infectious virus as compared with infectious virus. Almost all of the potentially infectious virus, but only approximately one-third of the infectious virus, was released from the infected cells.

MeSH Terms
Chymotrypsin/pharmacology Culture Techniques Cytopathogenic Effect, Viral Reoviridae/growth & development Virus Cultivation
Chemicals
Chymotrypsin
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Spendlove R S
Lennette E H
Knight C O
Chin J N
References (10)
10 references, click to expand
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    J Immunol. 1963 Apr;90:548-53 PMID: 14082016
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    J Immunol. 1963 Apr;90:554-60 PMID: 14082017
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    Virology. 1964 Apr;22:608-19 PMID: 14171600
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    Cancer Res. 1964 Nov;24:1826-33 PMID: 14230929
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.92.4.1036-1040.1966
Published
1966-10-00
Pages
1036-40
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC276374
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.92.4.1036-1040.1966 PMC Full Text View journal details
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