Abnormal forearm vascular responses in the carcinoid syndrome: the role of kinisns and kinin-generating system.

The Journal of clinical investigation ·Vol. 45 ·No. 11 ·1966-11-00 ·Pages 1685-99

Mason DT, Melmon KL

Abstract

暂无摘要

MeSH Terms

Adolescent Adult Bradykinin/pharmacology Cold Temperature Epinephrine/pharmacology Forearm/blood supply Hemodynamics/drug effects Humans Kallikreins/blood Malignant Carcinoid Syndrome Methoxamine/pharmacology Middle Aged Plethysmography Reflex Sympathetic Nervous System/drug effects Vascular Resistance/drug effects

Chemicals

Kallikreins Methoxamine Bradykinin Epinephrine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Mason D T

Melmon K L

References (35)

35 references, click to expand

EFFECTS OF GUANETHIDINE, RESERPINE, AND METHYLDOPA ON REFLEX VENOUS AND ARTERIAL CONSTRICTION IN MAN.
J Clin Invest. 1964 Jul;43:1449-63 PMID: 14192526
Investigation of arterial obstruction using a mercury-in-rubber strain gauge.
Am Heart J. 1961 Aug;62:194-205 PMID: 13715356
Carcinoid syndrome. Serotonin release induced with intravenous adrenaline or noradrenaline.
Lancet. 1961 Mar 18;1(7177):577-8 PMID: 13733800
A clinical, physiologic and biochemical study of patients with malignant carcinoid (argentaffinoma).
Am J Med. 1956 Apr;20(4):520-32 PMID: 13302231
Evidence for the release of bradykinin in carcinoid syndrome.
J Clin Invest. 1966 Feb;45(2):173-8 PMID: 5948092
RELEASE OF A KININ PEPTIDE IN THE CARCINOID SYNDROME.
Lancet. 1964 Mar 7;1(7332):514-7 PMID: 14100182
THE CARDIAC DISEASE ASSOCIATED WITH THE CARCINOID SYNDROME (CARCINOID HEART DISEASE).
Am J Med. 1964 Jan;36:5-34 PMID: 14117632
An unidentified depressor substance in certain tissue extracts.
J Physiol. 1931 Jun 6;72(1):74-87 PMID: 16994201
The relationship between glandular activity, bradykinin formation and functional vasodilatation in the submandibular salivary gland.
J Physiol. 1956 Nov 28;134(2):471-83 PMID: 13398926
Effect of local exercise of forearm muscles on forearm capacitance vessels.
J Appl Physiol. 1965 Sep;20(5):968-74 PMID: 5837624
The mechanism of facial flushes in the carcinoid syndrome.
Q J Med. 1962 Jan;31:103-23 PMID: 14492827
Paper chromatography of urinary indoles.
Lancet. 1955 Nov 12;269(6898):1009-11 PMID: 13272319
The nature of the kallidins released from human plasma by kallikreins and other enzymes.
Ann N Y Acad Sci. 1963 Feb 4;104:91-107 PMID: 13999415
The influence of tone upon responses of small and large vessels to serotonin.
Circ Res. 1959 Jan;7(1):123-30 PMID: 13619051
A unique syndrome associated with secretion of 5-hydroxytryptophan by metastatic gastric carcinoids.
Am J Med. 1962 Mar;32:333-42 PMID: 14480945
Action of adrenaline on limb blood vessels.
Br Med Bull. 1963 May;19:125-31 PMID: 14000248
The action of 5-hydroxytryptamine on the blood vessels of the human hand and forearm.
Br J Pharmacol Chemother. 1955 Dec;10(4):445-50 PMID: 13276601
Assay of serotonin and related metabolites, enzymes, and drugs.
Methods Biochem Anal. 1958;6:95-130 PMID: 13577424
EFFECTS OF BRADYKININ ON FOREARM VENOUS TONE AND VASCULAR RESISTANCE IN MAN.
Circ Res. 1965 Aug;17:106-13 PMID: 14334820
Hyperkinemia and cardiac failure in the carcinoid syndrome.
Am J Med. 1962 Jun;32:846-53 PMID: 13909647
Filling and emptying of the low-pressure blood vessels of the human forearm.
J Appl Physiol. 1966 Mar;21(2):573-82 PMID: 5934465
The variable arterial pressure response to serotonin in laboratory animals and man.
Circ Res. 1953 Jul;1(4):354-62 PMID: 13059881
NEW LIGHT ON CARCINOID FLUSH.
Lancet. 1964 Mar 7;1(7332):539-40 PMID: 14100196
Pressor amines and the carcinoid flush.
Ann Intern Med. 1963 May;58:818-28 PMID: 13930167
STUDIES ON DIGITALIS. X. EFFECTS OF OUABAIN ON FOREARM VASCULAR RESISTANCE AND VENOUS TONE IN NORMAL SUBJECTS AND IN PATIENTS IN HEART FAILURE.
J Clin Invest. 1964 Mar;43:532-43 PMID: 14135505
Carcinoid syndrome associated with hyperserotoninemia and normal 5-hydroxyindoleacetic acid excretion.
Am J Med. 1961 Jan;30:167-74 PMID: 13720235
Factors affecting the uptake of 5-hydroxytryptamine by human platelets in an inorganic medium.
J Biol Chem. 1960 Nov;235:3287-91 PMID: 13784118
THE CARCINOID SPECTRUM.
Gastroenterology. 1964 Jul;47:104-7 PMID: 14184337
Humoral agents and venous tone. Effects of catecholamines, 5-hydroxytryptamine, histamine, and nitritex.
Lancet. 1962 Dec 29;2(7270):1337-40 PMID: 13976913
The measurement of volume changes in human limbs.
J Physiol. 1953 Jul;121(1):1-27 PMID: 13085295
THE INFLUENCE OF THE COLLAPSIBILITY OF VEINS ON VENOUS PRESSURE, INCLUDING A NEW PROCEDURE FOR MEASURING TISSUE PRESSURE.
J Clin Invest. 1944 May;23(3):333-41 PMID: 16695110
On the excretion of 3-methoxy-4-hydroxymandelic acid in patients with serotonin producing tumours.
Scand J Clin Lab Invest. 1959;11:309-10 PMID: 13835405
Distinctive clinical and therapeutic aspects of the syndrome associated with bronchial carcinoid tumors.
Am J Med. 1965 Oct;39(4):568-81 PMID: 5831899
Further observations on patients with malignant carcinoid.
Am J Med. 1957 Jul;23(1):5-15 PMID: 13444286
The estimation of the kallidins in blood and urine.
Biochem Pharmacol. 1965 Jul;14(7):1161-3 PMID: 4285350

Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI105475

Published

1966-11-00

Pages

1685-99

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC292853

Subset

External Links

PubMed source DOI: 10.1172/JCI105475 PMC Full Text View journal details

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Abnormal forearm vascular responses in the carcinoid syndrome: the role of kinisns and kinin-generating system.

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