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PMID: 5914754 Published · ppublish English Journal Article

Antibody formation in nonimmune mouse peritoneal cells after incubation in gum containing antigen.

Science (New York, N.Y.) ·Vol. 153 ·No. 3738 ·1966-08-19 ·Pages 887-8

Bussard AE

Abstract

Peritoneal cells from normal mice in a semisolid medium containing sheep erythrocytes were incubated at 37 degrees C for 2 or 3 days. During this period, hemolytic antibodies developed spontaneously. Arguments are presented that true de novo synthesis of antibody has taken place in previously uncommitted cells.

MeSH Terms
Animals Antibody Formation Erythrocytes In Vitro Techniques Lymph Nodes Methylcellulose Mice Peritoneum Rabbits Resins, Plant Sheep Spleen
Chemicals
Resins, Plant Methylcellulose
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Bussard A E
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.153.3738.887
Published
1966-08-19
Pages
887-8
Language
English
Region
United States
NLM ID
0404511
Subset
IM
External Links
PubMed source DOI: 10.1126/science.153.3738.887 View journal details
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