Enzyme changes in neurons and glia during barbiturate sleep.

Science (New York, N.Y.) ·Vol. 151 ·No. 3716 ·1966-03-18 ·Pages 1394-5

Hamberger A, Hydén H, Lange PW

Abstract

During barbiturate sleep of rabbits, the succinoxidase activity in isolated neurons and glia from the caudal part of the reticular formation was lower than that during physiological sleep. No rhythmical, inverse enzyme changes were detected in barbiturate sleep in the neuron-glia unit, such as were found in physiological sleep.

MeSH Terms

Animals Barbiturates/pharmacology Electroencephalography In Vitro Techniques Neuroglia/enzymology Neurons/enzymology Pentobarbital/pharmacology Rabbits Reticular Formation/enzymology Sleep Succinate Dehydrogenase/metabolism

Chemicals

Barbiturates Succinate Dehydrogenase Pentobarbital

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Hamberger A

Hydén H

Lange P W

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.151.3716.1394

Published

1966-03-18

Pages

1394-5

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.151.3716.1394 View journal details

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