Thyrocalcitonin: inhibitor of bone resorption in tissue culture.

Science (New York, N.Y.) ·Vol. 150 ·No. 3702 ·1965-12-10 ·Pages 1465-7

Friedman J, Raisz LG

Abstract

A partially purified protein from thyroid glands of rats inhibits release of calcium from long bones of embryo rats in tissue culture. Inhibition was more easily detected when resorption of bone was stimulated by parathyroid hormone.

MeSH Terms

Animals Bone Resorption/drug effects Bone and Bones/embryology Calcitonin/pharmacology Calcium/metabolism Calcium Isotopes Chromatography, Ion Exchange Culture Media Culture Techniques Female Male Parathyroid Hormone/pharmacology Pregnancy Rats

Chemicals

Calcium Isotopes Culture Media Parathyroid Hormone Calcitonin Calcium

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Friedman J

Raisz L G

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.150.3702.1465

Published

1965-12-10

Pages

1465-7

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.150.3702.1465 View journal details

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Thyrocalcitonin: inhibitor of bone resorption in tissue culture.

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