Primary immune reactions in organ cultures.

Science (New York, N.Y.) ·Vol. 149 ·No. 3687 ·1965-08-27 ·Pages 991-3

Globerson A, Auerbach R

Abstract

Primary immune reactions were initiated and maintained in vitro. Spleen explants from mice treated with either phytohemagglutinin or adjuvant were stimulated to form hemagglutinins and hemolysins, whereas no treatment of spleen donors was necessary to invoke a "graft-versus-host" response which led to specific splenomegly.

MeSH Terms

Adjuvants, Immunologic/pharmacology Animals Antibody Formation/physiology Cell Differentiation Culture Techniques Erythrocytes Hemagglutination Lectins/pharmacology Lymphoid Tissue/cytology Mice Sheep Spleen/cytology,embryology,physiology Transplantation Immunology

Chemicals

Adjuvants, Immunologic Lectins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Globerson A

Auerbach R

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.149.3687.991

Published

1965-08-27

Pages

991-3

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.149.3687.991 View journal details

Analysis Services

Primary immune reactions in organ cultures.

Contact

WeChat Official Account