Release of alkaline phosphatase from membranes by a phosphatidylinositol-specific phospholipase C.

The Biochemical journal ·Vol. 167 ·No. 1 ·1977-10-01 ·Pages 281-4

Low MG, Finean JB

Abstract

Purified phosphatidylinositol-specific phospholipase C from Staphylococcus aureus released a substantial proportion of the total alkaline phosphatase activity from a wide range of tissues from several mammalian species. Co-purification of the phospholipase C and alkaline phosphatase-releasing activities and the inhibition of both these activities by iso-osmotic salt solutions suggested that the releasing effect was unlikely to be due to a contaminant.

MeSH Terms

Alkaline Phosphatase/metabolism Animals Guinea Pigs Membranes/drug effects,enzymology Phosphatidylinositols Phospholipases/pharmacology Rabbits Staphylococcus aureus/enzymology Swine

Chemicals

Phosphatidylinositols Phospholipases Alkaline Phosphatase

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Low M G

Finean J B

References (12)

12 references, click to expand

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Partial purification and properties of two phospholipases of Bacillus cereus.
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Studies on phosphatidylinositol phosphodiesterase (phospholipase C type) of Bacillus cereus. I. purification, properties and phosphatase-releasing activity.
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Modification of erythrocyte membranes by a purified phosphatidylinositol-specific phospholipase C (Staphylococcus aureus).
Biochem J. 1977 Feb 15;162(2):235-40 PMID: 849283
Enzymic release of enteropeptidase from isolated rat duodenal brush borders.
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On the distribution of enterokinase in porcine intestine and on its subcellular localization.
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Phosphatidylinositol cleavage catalysed by the soluble fraction from lymphocytes. Activity at pH5.5 and pH7.0.
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Biochem J. 1974 Jul;141(1):273-82 PMID: 4455205
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Biochim Biophys Acta. 1972 Jan 17;255(1):114-25 PMID: 5010988
Purification by affinity chromatography of phospholipase C from Bacillus cereus.
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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj1670281

Published

1977-10-01

Pages

281-4

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1183647

Subset

External Links

PubMed source DOI: 10.1042/bj1670281 PMC Full Text View journal details

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Release of alkaline phosphatase from membranes by a phosphatidylinositol-specific phospholipase C.

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