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PMID: 5880363 Published · ppublish English Journal Article

Voltage clamp experiments on internally perfused giant axons.

The Journal of physiology ·Vol. 180 ·No. 4 ·1965-10-00 ·Pages 788-820

Chandler WK, Meves H

Abstract

暂无摘要

MeSH Terms
Animals Axons/physiology Cesium/pharmacology Chlorides/pharmacology Electrophysiology Hydrogen-Ion Concentration In Vitro Techniques Lithium/pharmacology Mollusca Neural Conduction Perfusion Potassium Chloride/pharmacology Rubidium/pharmacology Sodium/pharmacology Sucrose/pharmacology
Chemicals
Chlorides Cesium Sucrose Potassium Chloride Lithium Sodium Rubidium
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Chandler W K
Meves H
References (31)
31 references, click to expand
  1. Sodium currents in the myelinated nerve fibre of Xenopus laevis investigated with the voltage clamp technique.
    J Physiol. 1959 Oct;148:188-200 PMID: 13817145
  2. The measurement of sodium and potassium activities in the squid axon by means of cation-selective glass micro-electrodes.
    J Physiol. 1961 Apr;156:314-35 PMID: 13714453
  3. Replacement of the axoplasm of giant nerve fibres with artificial solutions.
    J Physiol. 1962 Nov;164:330-54 PMID: 13969166
  4. EFFECTS OF VARIOUS POTASSIUM SALTS AND PROTEASES UPON EXCITABILITY OF INTRACELLULARLY PERFUSED SQUID GIANT AXONS.
    Proc Natl Acad Sci U S A. 1964 Sep;52:804-10 PMID: 14212560
  5. SODIUM CONDUCTANCE SHIFT IN AN AXON INTERNALLY PERFUSED WITH A SUCROSE AND LOW-POTASSIUM SOLUTION.
    J Physiol. 1964 Aug;172:163-73 PMID: 14205014
  6. INTRACELLULAR PERFUSION OF CHILEAN GIANT SQUID AXONS.
    Science. 1964 Sep 18;145(3638):1313-5 PMID: 14173418
  7. Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo.
    J Physiol. 1952 Apr;116(4):449-72 PMID: 14946713
  8. The effects of changes in internal ionic concentrations on the electrical properties of perfused giant axons.
    J Physiol. 1962 Nov;164:355-74 PMID: 13969165
  9. THE SPECIFICITY OF THE INITIAL CURRENT IN MYELINATED NERVE FIBRES OF XENOPUS LAEVIS. VOLTAGE CLAMP EXPERIMENTS.
    J Physiol. 1963 Nov;169:438-44 PMID: 14079680
  10. THE RUBIDIUM AND POTASSIUM PERMEABILITY OF FROG MUSCLE MEMBRANE.
    J Physiol. 1964 Dec;175:134-59 PMID: 14241154
  11. Ionic current measurements in the squid giant axon membrane.
    J Gen Physiol. 1960 Sep;44:123-67 PMID: 13694548
  12. THE EFFECT OF DILUTING THE INTERNAL SOLUTION ON THE ELECTRICAL PROPERTIES OF A PERFUSED GIANT AXON.
    J Physiol. 1964 Apr;170:541-60 PMID: 14165694
  13. Movement of radioactive potassium and membrane current in a giant axon.
    J Physiol. 1953 Aug;121(2):403-14 PMID: 13085343
  14. Current-voltage relations in the lobster giant axon membrane under voltage clamp conditions.
    J Gen Physiol. 1962 Jul;45:1217-38 PMID: 14452758
  15. CAESUM IONS DO NOT PASS THE MEMBRANE OF THE GIANT AXON.
    Proc Natl Acad Sci U S A. 1964 Nov;52:1177-83 PMID: 14231437
  16. INTERNALLY PERFUSED SQUID AXONS STUDIED UNDER VOLTAGE CLAMP CONDITIONS. II. RESULTS. THE EFFECTS OF INTERNAL POTASSIUM AND SODIUM ON MEMBRANE ELECTRICAL CHARACTERISTICS.
    J Cell Physiol. 1964 Dec;64:429-43 PMID: 14245458
  17. The components of membrane conductance in the giant axon of Loligo.
    J Physiol. 1952 Apr;116(4):473-96 PMID: 14946714
  18. The dual effect of membrane potential on sodium conductance in the giant axon of Loligo.
    J Physiol. 1952 Apr;116(4):497-506 PMID: 14946715
  19. THE INFLUENCE OF SODIUM-FREE SOLUTIONS ON THE MEMBRANE POTENTIAL OF FROG MUSCLE FIBERS.
    J Gen Physiol. 1963 Sep;47:117-32 PMID: 14060441
  20. DEPENDENCE OF RESTING AND ACTION POTENTIALS ON INTERNAL POTASSIUM IN PERFUSED SQUID GIANT AXONS.
    J Physiol. 1963 Nov;169:91-115 PMID: 14078066
  21. Derivation of an equation for the diffusion potential.
    Nature. 1960 Dec 10;188:944-5 PMID: 13733316
  22. The ionic requirements for the production of action potentials in crustacean muscle fibres.
    J Physiol. 1958 Aug 6;142(3):516-43 PMID: 13576452
  23. RESTING AND ACTION POTENTIAL OF SQUID GIANT AXONS INTRACELLULARLY PERFUSED WITH SODIUM-RICH SOLUTIONS.
    Proc Natl Acad Sci U S A. 1963 Oct;50:619-26 PMID: 14077488
  24. The action of calcium on the electrical properties of squid axons.
    J Physiol. 1957 Jul 11;137(2):218-44 PMID: 13449874
  25. Electronic measurement of the intracellular concentration and net flux of sodium in the squid axon.
    J Gen Physiol. 1961 Sep;45:77-92 PMID: 13772321
  26. Leakage current rectification in the squid giant axon.
    Nature. 1961 Jun 3;190:883-5 PMID: 14448232
  27. Measurement of current-voltage relations in the membrane of the giant axon of Loligo.
    J Physiol. 1952 Apr;116(4):424-48 PMID: 14946712
  28. Cation selective glass electrodes and their mode of operation.
    Biophys J. 1962 Mar;2(2 Pt 2):259-323 PMID: 13889686
  29. The effect of changing the internal solution on sodium inactivation and related phenomena in giant axons.
    J Physiol. 1965 Oct;180(4):821-36 PMID: 5880364
  30. Potassium ion current in the squid giant axon: dynamic characteristic.
    Biophys J. 1960 Sep;1:1-14 PMID: 13694549
  31. The effect of sodium ions on the electrical activity of giant axon of the squid.
    J Physiol. 1949 Mar 1;108(1):37-77 PMID: 18128147
Article Info
Journal
The Journal of physiology
Abbr.
J Physiol
ISSN
0022-3751
DOI
10.1113/jphysiol.1965.sp007732
Published
1965-10-00
Pages
788-820
Language
English
Region
England
NLM ID
0266262
PMCID
PMC1357423
Subset
IM
External Links
PubMed source DOI: 10.1113/jphysiol.1965.sp007732 PMC Full Text View journal details
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