Cytotoxic effects of 1-beta-D-arabinofuranosyl-5-fluorocytosine and of 1-beta-D-arabinofuranosylcytosine in proliferating tissues in mice.

Animals Antimetabolites Carbon Isotopes Cell Division/drug effects Cytarabine/administration & dosage,toxicity Cytosine/administration & dosage,toxicity DNA/biosynthesis Duodenum/drug effects Epithelium/drug effects Fluorine/administration & dosage,toxicity Intestine, Small/drug effects Male Mice Mitosis/drug effects Phosphorus/antagonists & inhibitors,metabolism Phosphorus Isotopes RNA/biosynthesis Spleen/drug effects Thymidine/antagonists & inhibitors Thymus Gland/drug effects

Antimetabolites Carbon Isotopes Phosphorus Isotopes Cytarabine Phosphorus Fluorine RNA Cytosine DNA Thymidine