Cystic fibrosis heterozygosity in the pathogenesis of allergy.

Lancet (London, England) ·Vol. 1 ·No. 7967 ·1976-05-08 ·Pages 990-1

Warner JO, Norman AP, Soothill JF

Abstract

47% of cystic fibrosis (C.F.) heterozygotes had positive prick skin tests of 1 or more of 9 antigens and 53% had histories of allergic disease, both occurring significantly more often than in a control group. Since 1 in 20 of the population are C.F. carriers, this would contribute to allergy in the community.

MeSH Terms

Allergens Cystic Fibrosis/genetics Female Heterozygote Homozygote Humans Hypersensitivity/diagnosis,etiology,genetics Male Skin Tests

Chemicals

Allergens

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Warner J O

Norman A P

Soothill J F

Article Info

Journal

Lancet (London, England)

Abbr.

Lancet

ISSN

0140-6736

DOI

10.1016/s0140-6736(76)91862-6

Published

1976-05-08

Pages

990-1

Language

English

Region

England

NLM ID

2985213R

Subset

External Links

PubMed source DOI: 10.1016/s0140-6736(76)91862-6 View journal details

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Cystic fibrosis heterozygosity in the pathogenesis of allergy.

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