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PMID: 5726 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Regulation of guanylate and adenylate cyclase activities by lysolecithin.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 73 ·No. 5 ·1976-05-00 ·Pages 1586-90

Shier WT, Baldwin JH, Nilsen-Hamilton M, Hamilton RT, Thanassi NM

Abstract

The guanylate cyclase activity [GTP pyrophosphate-lyase (cyclizing), EC 4.6.1.2] in membrane preparations from 3T3 mouse fibroblasts is stimulated approximately 5-fold by lysolecithin at concentrations of 100 mug/ml and above.

MeSH Terms
Adenylyl Cyclase Inhibitors Cell Line Cell Membrane/enzymology Cell Transformation, Neoplastic Fluorides/pharmacology Guanylate Cyclase/metabolism Lipids/pharmacology Lysophosphatidylcholines/analogs & derivatives,pharmacology Polyethylene Glycols/pharmacology
Chemicals
Adenylyl Cyclase Inhibitors Lipids Lysophosphatidylcholines Polyethylene Glycols Guanylate Cyclase Fluorides
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Shier W T
Baldwin J H
Nilsen-Hamilton M
Hamilton R T
Thanassi N M
References (29)
29 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.73.5.1586
Published
1976-05-00
Pages
1586-90
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC430343
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.73.5.1586 PMC Full Text View journal details
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