Evidence for a role of RNA in eukaryotic chromosome structure. Metabolically stable, small nuclear RNA species are covalently linked to chromosomal DNA in HeLa cells.

Binding Sites Cell Cycle Cell Nucleus/analysis Chromatin/analysis Chromosomes, Human/analysis DNA/analysis DNA Replication HeLa Cells/analysis,cytology Humans Molecular Weight Nucleic Acid Conformation Nucleic Acid Denaturation Nucleic Acid Hybridization RNA/analysis Transcription, Genetic

Chromatin RNA DNA