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PMID: 5678443 Published · ppublish English Journal Article

The turnover of nuclear DNA-like RNA in HeLa cells.

The Journal of cell biology ·Vol. 39 ·No. 1 ·1968-10-00 ·Pages 112-8

Soeiro R, Vaughan MH, Warner JR, Darnell JE

Abstract

The subcellular distribution of various types of RNA in HeLa cells is described. In addition, the relative rate of synthesis of the major classes of nuclear RNA has been determined. From these experiments it can be deduced that the heterogeneous nuclear RNA fraction is rapidly synthesized and degraded within the cell nucleus.

MeSH Terms
Carbon Isotopes Cell Nucleus/metabolism DNA, Neoplasm/metabolism HeLa Cells/metabolism Humans Phosphorus Isotopes RNA, Neoplasm/biosynthesis,metabolism Uridine/metabolism
Chemicals
Carbon Isotopes DNA, Neoplasm Phosphorus Isotopes RNA, Neoplasm Uridine
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Soeiro R
Vaughan M H
Warner J R
Darnell J E
References (28)
28 references, click to expand
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Article Info
Journal
The Journal of cell biology
Abbr.
J Cell Biol
ISSN
0021-9525
DOI
10.1083/jcb.39.1.112
Published
1968-10-00
Pages
112-8
Language
English
Region
United States
NLM ID
0375356
PMCID
PMC2107516
Subset
IM
External Links
PubMed source DOI: 10.1083/jcb.39.1.112 PMC Full Text View journal details
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