Carcinogenic action of 4-acetamidostilbene and the N-hydroxy derivative in the rat.

British journal of cancer ·Vol. 22 ·No. 1 ·1968-03-00 ·Pages 133-44

Baldwin RW, Cunningham GJ, Smith WR, Surtees SJ

Abstract

暂无摘要

MeSH Terms

Animals Body Weight/drug effects Carcinoma, Squamous Cell/chemically induced,pathology Ear Neoplasms/chemically induced Female Injections, Intraperitoneal Injections, Subcutaneous Male Rats Sebaceous Gland Neoplasms/chemically induced Stilbenes/administration & dosage

Chemicals

Stilbenes

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Baldwin R W

Cunningham G J

Smith W R

Surtees S J

References (12)

12 references, click to expand

THE COMPARATIVE CARCINOGENICITIES OF 2-ACETYLAMINOFLUORENE AND ITS N-HYDROXY METABOLITE IN MICE, HAMSTERS, AND GUINEA PIGS.
Cancer Res. 1964 Dec;24:2018-31 PMID: 14252144
The conversion of noncarcinogenic aromatic amides to carcinogenic arylhydroxamic acids by synthetic N-hydroxylation.
Cancer Res. 1967 Aug;27(8):1443-55 PMID: 6047873
Leukemia induced by 7,12-dimethylbenz[alpha]-anthracene in germfree rats.
J Natl Cancer Inst. 1967 Jul;39(1):135-41 PMID: 5230067
N-Hydroxy-2-acetylaminofluorene: a metabolite of 2-acetylaminofluorene with increased carcinogenic activity in the rat.
Cancer Res. 1961 Jul;21:815-24 PMID: 13770754
The carcinogenic action of aminostilbene derivatives in rats maintained on high and low protein diets.
Br J Cancer. 1952 Dec;6(4):392-9 PMID: 13032310
Multipotential carcinogenicity of urethan in the Sprague-Dawley rat.
Cancer Res. 1962 Dec;22:1362-71 PMID: 13984878
CARCINOGENESIS AND INHIBITION OF THE WALKER 256 TUMOR IN THE RAT BY TRANS-4-ACETYLAMINOSTILBENE, ITS N-HYDROXY METABOLITE, AND RELATED COMPOUNDS.
Cancer Res. 1964 Jan;24:128-43 PMID: 14106156
Auditory canal structures in rats as altered by aging and by the administration of tris(p-aminophenyl)carbonium pamoate.
Cancer Res. 1966 Aug;26(8):1625-32 PMID: 5923160
The early changes produced in the auditory sebaceous gland (Zymbal's gland) of the rat by 2-acetylaminofluorene.
Cancer Res. 1955 Mar;15(3):139-42 PMID: 14352202
Effect of dose and hormones on tumor production in rats given emulsified 9, 10-dimethyl-1,2-benzanthracene intravenously.
Cancer Res. 1953 Jul;13(7:1):503-6 PMID: 13067066
The carcinogenic action of benzidine.
Cancer. 1950 Sep;3(5):789-804 PMID: 14772711
N-Hydroxylation: A new metabolic reaction observed in the rat with the carcinogen 2-acetylaminofluorene.
J Biol Chem. 1960 Mar;235:885-8 PMID: 13812621

Article Info

Journal

British journal of cancer

Abbr.

Br J Cancer

ISSN

0007-0920

DOI

10.1038/bjc.1968.19

Published

1968-03-00

Pages

133-44

Language

English

Region

England

NLM ID

0370635

PMCID

PMC2008229

Subset

External Links

PubMed source DOI: 10.1038/bjc.1968.19 PMC Full Text View journal details

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Carcinogenic action of 4-acetamidostilbene and the N-hydroxy derivative in the rat.

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