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PMID: 5637358 Published · ppublish English Journal Article

The carbohydrate components of hydrolysates of gastric secretion and extracts from mucous glands of the gastric body mucosa and antrum.

The Biochemical journal ·Vol. 106 ·No. 2 ·1968-01-00 ·Pages 523-9

Schrager J, Oates MD

Abstract

1. The sugars and amino sugars of hydrolysates of gastric secretion were determined by gas-liquid chromatography. 2. All the gastric aspirations examined showed on hydrolysis the presence of fucose, galactose, mannose, glucose, galactosamine, glucosamine, N-acetylneuraminic acid and sulphate. 3. Galactose and glucosamine were always found in equimolar amounts, but the galactose/galactosamine ratio in different aspirations was 2:1, 3:1, 4:1 or 5:1. Repeated gastric aspirations of each subject examined showed constant ratios of these carbohydrate components. 4. Fucose and sialic acid appear to be related to glucosamine and galactosamine respectively. 5. The carbohydrate components of extracts from the mucous glands of the body mucosa and antrum did not differ from those of gastric secretion.

MeSH Terms
Carbohydrates/analysis Chromatography, Gas Drainage Gastrectomy Gastric Juice/analysis Gastric Mucosa/analysis Hexosamines/analysis Hexoses/analysis Histamine/pharmacology Humans Insulin/pharmacology Mucus/analysis Neuraminic Acids/analysis Starvation
Chemicals
Carbohydrates Hexosamines Hexoses Insulin Neuraminic Acids Histamine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Schrager J
Oates M D
References (6)
6 references, click to expand
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  2. Quantitative paper partition chromatography of sialic acids.
    Nature. 1958 Apr 19;181(4616):1154-5 PMID: 13541412
  3. The thiobarbituric acid assay of sialic acids.
    J Biol Chem. 1959 Aug;234(8):1971-5 PMID: 13672998
  4. Chromatographic observations of human gastric mucopolysaccharides.
    Nature. 1963 Jun 1;198:899-900 PMID: 13992412
  5. SULPHATED MUCOPOLYSACCHARIDES OF THE GASTRIC SECRETION.
    Nature. 1964 Feb 15;201:702-4 PMID: 14134716
  6. THE FRACTIONATION AND CHARACTERISATION OF THE ACID POLYSACCHARIDES IN HUMAN GASTRIC JUICE.
    Acta Chem Scand. 1965;19:797-9 PMID: 14320660
Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
Published
1968-01-00
Pages
523-9
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1198533
Subset
IM
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