Purpura, arthralgia, and IgM-IgM cryoglobulinemia with rheumatoid factor acrivity. Response to cyclophosphamide and splenectomy.

Agglutination Tests Blood Protein Disorders/therapy Cryoglobulins Cyclophosphamide/therapeutic use Glomerulonephritis/complications,drug therapy,pathology,therapy Humans Immunoelectrophoresis Immunoglobulin G Immunoglobulin M Joint Diseases/complications,drug therapy,therapy Kidney Glomerulus/pathology Latex Fixation Tests Male Middle Aged Purpura/complications,drug therapy,pathology,therapy Rheumatoid Factor Splenectomy

Cryoglobulins Immunoglobulin G Immunoglobulin M Cyclophosphamide Rheumatoid Factor