A role for brown adipose tissue in diet-induced thermogenesis.

Nature ·Vol. 281 ·No. 5726 ·1979-09-06 ·Pages 31-5

Rothwell NJ, Stock MJ

Abstract

Measurement of energy balance during voluntary overeating in rats unequivocally establishes the quantitative importance of diet-induced thermogenesis in energy balance. Like cold-induced thermogenesis, this form of heat production involves changes in the activity of the sympathetic nervous system and brown adipose tissue which suggest that this tissue may determine metabolic efficiency and resistance to obesity.

MeSH Terms

Adipose Tissue, Brown/physiology Animals Body Temperature Regulation Diet Disease Models, Animal Energy Metabolism Humans Lipid Mobilization Male Norepinephrine/pharmacology Obesity/metabolism Oxygen Consumption/drug effects Rats Sympathetic Nervous System/physiology

Chemicals

Norepinephrine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Rothwell N J

Stock M J

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/281031a0

Published

1979-09-06

Pages

31-5

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/281031a0 View journal details

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A role for brown adipose tissue in diet-induced thermogenesis.

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