Appearance of defective virions in clones of reovirus.

Journal of virology ·Vol. 6 ·No. 5 ·1970-11-00 ·Pages 693-4

Nonoyama M, Graham AF

Abstract

Virus obtained from five plaques of reovirus was serially passaged in L cells. Defective virions arose in each clone by the seventh passage. Such defective virions lacked the largest of the 10 segments of the double-stranded ribonucleic acid genome.

MeSH Terms

Acrylates Centrifugation, Density Gradient Cesium Chlorides Chymotrypsin Dactinomycin Electrophoresis Gels Genetics, Microbial L Cells RNA, Viral/analysis Reoviridae/growth & development,isolation & purification Tritium Uridine Virus Replication

Chemicals

Acrylates Chlorides Gels RNA, Viral Tritium Dactinomycin Cesium Chymotrypsin Uridine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Nonoyama M

Graham A F

References (3)

3 references, click to expand

RNA polymerase activity in purified reoviruses.
Proc Natl Acad Sci U S A. 1968 Dec;61(4):1462-9 PMID: 4179180
Polypeptide components of virions, top component and cores of reovirus type 3.
Virology. 1969 Dec;39(4):791-810 PMID: 4311639
Defective virions of reovirus.
J Virol. 1970 Aug;6(2):226-36 PMID: 4101106

Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.6.5.693-694.1970

Published

1970-11-00

Pages

693-4

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC376176

Subset

External Links

PubMed source DOI: 10.1128/JVI.6.5.693-694.1970 PMC Full Text View journal details

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Appearance of defective virions in clones of reovirus.

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