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PMID: 5464292 Published · ppublish English Journal Article

Serological study of a mutant of herpesvirus unable to stimulate thymidine kinase.

Journal of virology ·Vol. 5 ·No. 6 ·1970-06-00 ·Pages 817-8

Buchan A, Watson DH, Dubbs DR, Kit S

Abstract

A mutant of herpes simplex virus which was unable to produce thymidine kinase also failed to produce an antigen which blocked the enzyme-inhibiting activity of antiserum prepared against virus-infected cells.

MeSH Terms
Animals Antigens/analysis Cell Line Cricetinae Enzyme Induction Genetics, Microbial Herpesviridae/enzymology,immunology Hot Temperature Immune Sera Kidney Mutation Thymidine Kinase/metabolism
Chemicals
Antigens Immune Sera Thymidine Kinase
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Buchan A
Watson D H
Dubbs D R
Kit S
References (6)
6 references, click to expand
  1. A virus-specific thymidine kinase in BHK-21 cells infected with herpes simplex virus.
    Virology. 1967 Jan;31(1):120-8 PMID: 4289344
  2. The separation of herpes virus-specific antigens by polyacrylamide gel electrophoresis.
    J Gen Virol. 1969 Mar;4(2):151-61 PMID: 4306293
  3. The immunological specificity of thymidine kinases in cells infected by viruses of the herpes group.
    J Gen Virol. 1969 Apr;4(3):461-3 PMID: 4306717
  4. Altered properties of thymidine kinase after infection of mouse fibroblast cells with herpes simplex virus.
    J Virol. 1967 Feb;1(1):238-40 PMID: 4318945
  5. AN ELECTRON MICROSCOPE STUDY OF THE ATTACHMENT AND PENETRATION OF HERPES VIRUS IN BHK21 CELLS.
    Virology. 1963 Sep;21:112-23 PMID: 14062901
  6. MUTANT STRAINS OF HERPES SIMPLEX DEFICIENT IN THYMIDINE KINASE-INDUCING ACTIVITY.
    Virology. 1964 Apr;22:493-502 PMID: 14166109
Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
Published
1970-06-00
Pages
817-8
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC376074
Subset
IM
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