Virus-induced hydrocephalus: development of aqueductal stenosis in hamsters after mumps infection.

Science (New York, N.Y.) ·Vol. 157 ·No. 3792 ·1967-09-01 ·Pages 1066-7

Johnson RT, Johnson KP, Edmonds CJ

Abstract

Hydrocephalus developed as a sequela of mumps virus infections of suckling hamsters. The initial infection after intracerebral inoculation was limited largely to ependymal cells lining the ventricles. This infection was clinically inapparent but later resulted in a noninflammatory stenosis or occlusion of the aqueduct of Sylvius.

MeSH Terms

Animals Cerebral Ventricles/pathology Cricetinae Encephalitis Ependyma/pathology Fluorescent Antibody Technique Hydrocephalus/etiology Mumps/complications,immunology Neutralization Tests

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Johnson R T

Johnson K P

Edmonds C J

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.157.3792.1066

Published

1967-09-01

Pages

1066-7

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.157.3792.1066 View journal details

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Virus-induced hydrocephalus: development of aqueductal stenosis in hamsters after mumps infection.

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