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PMID: 5335972 Published · ppublish English Journal Article

Postirradiation cell division in 5-fluorouracil-pre-treated Escherichia coli.

Journal of bacteriology ·Vol. 93 ·No. 2 ·1967-02-00 ·Pages 749-53

Ben-Ishai R, Zeevi N

Abstract

The correlation between 5-fluorouracil-induced resistance to ultraviolet (UV) light and the ability of bacterial cells to repair irradiation damage was investigated in various strains of Escherichia coli. Preincubation with 5-fluorouracil did not influence the dark-repair mechanism. It affected, however, the UV light-induced damage of cell division in filament-forming strains. It is suggested that the delay in postirradiation macromolecular synthesis of 5-fluorouracil-pretreated bacteria plays a decisive role in the recovery process leading to cross cell wall-forming ability in the damaged strains.

MeSH Terms
Cell Division/drug effects,radiation effects Escherichia coli/drug effects,radiation effects Fluorouracil/pharmacology Microscopy Radiation Effects Ultraviolet Rays
Chemicals
Fluorouracil
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Ben-Ishai R
Zeevi N
References (19)
19 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
Published
1967-02-00
Pages
749-53
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC276504
Subset
IM
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