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PMID: 5333756 Published · ppublish English Journal Article Review

Keto-aldehydes and cell division.

Science (New York, N.Y.) ·Vol. 155 ·No. 3762 ·1967-02-03 ·Pages 539-41

Szent-Györgyi A, Együd LG, McLaughlin JA

Abstract

Many problems are left open in this article. Its publication may be excused by the suffering cancer causes, which urges the researcher to publish as soon as he thinks he may have found a new trail, which also may be taken by others. What emerges clearly is that SH groups, with their specific reactivities, offer a hopeful target in the search for cancerostatic substances, among which the natural repressor of cell division may hold out the most promise. The glyoxal derivatives also have antiviral properties (7, 16) and may be in the center of a hitherto unknown system of equilibria which deserves a thorough study. The low molecular weight of the glyoxal derivative reported justifies the hope of an early clarification of its structure, as well as its synthesis (17).

MeSH Terms
Aldehydes/pharmacology Animals Cattle Cell Division/drug effects Liver/drug effects
Chemicals
Aldehydes
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Szent-Györgyi A
Együd L G
McLaughlin J A
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1967-02-03
Pages
539-41
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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