Replication of repetitious DNA and the S period.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 67 ·No. 1 ·1970-09-00 ·Pages 448-55

Comings DE, Mattoccia E

Abstract

The renaturation kinetics of labeled DNA derived from synchronized Chinese hamster cells indicate that the three classes of repetitious DNA replicate uniformly throughout the S period, and that a piece of repetitious DNA may occur at or near the beginning of each replicon. Studies with mouse-cell DNA suggest that mouse satellite DNA replicates when euchromatin replicates.

MeSH Terms

Animals Carbon Isotopes Cell Line Cricetinae Culture Techniques DNA Replication Fibroblasts Kinetics Lung Mice Nucleic Acid Denaturation Thymidine Time Factors Tritium

Chemicals

Carbon Isotopes Tritium Thymidine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Comings D E

Mattoccia E

References (13)

13 references, click to expand

Synchronization of Chinese hamster cells by reversal of colcemid inhibition.
Exp Cell Res. 1965 Dec;40(3):660-4 PMID: 5325429
Mouse satellite DNA. Further studies on its biological and physical characteristics and its intracellular localization.
J Mol Biol. 1967 Jul 28;27(2):289-302 PMID: 6048984
Studies on the intranuclear distribution and properties of mouse satellite DNA.
Biochim Biophys Acta. 1968 Jun 18;161(1):76-93 PMID: 5690801
Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms.
Science. 1968 Aug 9;161(3841):529-40 PMID: 4874239
RNA replication by nuclear satellite DNA in different mouse cells.
Biochem Biophys Res Commun. 1968 Nov 25;33(4):696-701 PMID: 5697274
RNA-DNA hybrids at the cytological level.
Nature. 1969 Aug 9;223(5206):582-7 PMID: 5799530
Isolated mammalian metaphase chromosomes. II. Fractionated chromosomes of mouse and Chinese hamster cells.
J Mol Biol. 1969 Mar 14;40(2):203-16 PMID: 5391786
On the duplication of ribosomal RNA cistrons in Chinese hamster cells.
Eur J Biochem. 1969 Dec;11(3):419-23 PMID: 5392317
Chromosomal localization of mouse satellite DNA.
Science. 1970 Jun 12;168(3937):1356-8 PMID: 5462793
Localization of mouse satellite DNA in constitutive heterochromatin.
Exp Cell Res. 1970 Jan;59(1):69-75 PMID: 4194430
Studies on unbalanced growth in tissue culture. I. Induction and consequences of thymidine deficiency.
Cancer Res. 1960 Dec;20:1584-91 PMID: 13744520
STUDIES ON SYNCHRONOUS DIVISION OF TISSUE CULTURE CELLS INITIATED BY EXCESS THYMIDINE.
Exp Cell Res. 1964 Jan;33:301-9 PMID: 14109144
NUCLEOTIDE COMPOSITION OF SHORT SEGMENTS OF DNA MOLECULES.
J Mol Biol. 1965 Feb;11:223-37 PMID: 14290342

Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.67.1.448

Published

1970-09-00

Pages

448-55

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC283225

Subset

External Links

PubMed source DOI: 10.1073/pnas.67.1.448 PMC Full Text View journal details

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