Amino acid sequence of bovine thyrocalcitonin.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 63 ·No. 3 ·1969-07-00 ·Pages 940-7

Brewer HB, Ronan R

Abstract

Bovine thyrocalcitonin has been isolated in homogeneous form, and its complete amino acid sequence determined. The bovine hormone is a singlechain 32 amino acid polypeptide. It contains a 1-7 amino terminal disulfide bridge, and the carboxyl terminal amino acid is prolinamide. The bovine thyrocalcitonin sequence differs from the porcine sequence by three amino acid residues and from the human sequence by 18 amino acid residues.

MeSH Terms

Amino Acid Sequence Animals Calcitonin/analysis Cattle Chromatography, Gel Chromatography, Ion Exchange Methods

Chemicals

Calcitonin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Brewer H B

Ronan R

References (13)

13 references, click to expand

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Nature. 1967 Oct 28;216(5113):332-5 PMID: 4168590
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J Am Chem Soc. 1968 May 8;90(10):2704-6 PMID: 5651075
The amino acid sequence of porcine thyrocalcitonin.
Proc Natl Acad Sci U S A. 1968 Apr;59(4):1321-8 PMID: 5240032
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Helv Chim Acta. 1968;51(1):214-7 PMID: 5681981
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J Biol Chem. 1968 Nov 10;243(21):5739-47 PMID: 5699061
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Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.63.3.940

Published

1969-07-00

Pages

940-7

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC223543

Subset

External Links

PubMed source DOI: 10.1073/pnas.63.3.940 PMC Full Text View journal details

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Amino acid sequence of bovine thyrocalcitonin.

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