Primary structure of wheat germ phenylalanine transfer RNA.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 62 ·No. 3 ·1969-03-00 ·Pages 941-5

Dudock BS, Katz G, Taylor EK, Holley RW

Abstract

The complete nucleotide sequence of wheat germ phenylalanine transfer RNA (tRNA(Phe)) is presented. This RNA, which is an acceptable substrate for yeast phenylalanine tRNA synthetase, has a structure very similar to that of yeast tRNA(Phe). Only 16 of the 76 nucleotides are different, and all but two of the nucleotide changes are located in regions that are doublestranded in the cloverleaf model. The two changes in single-stranded regions involve minor modifications of the same nucleotide. The dihydrouridine loop and its supporting stem are completely free of nucleotide changes.

MeSH Terms

Amino Acid Sequence Chromatography Ligases Methods Models, Chemical Nucleotides/analysis Phenylalanine RNA, Transfer/analysis,isolation & purification Triticum

Chemicals

Nucleotides Phenylalanine RNA, Transfer Ligases

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Dudock B S

Katz G

Taylor E K

Holley R W

References (14)

14 references, click to expand

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Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.62.3.941

Published

1969-03-00

Pages

941-5

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC223689

Subset

External Links

PubMed source DOI: 10.1073/pnas.62.3.941 PMC Full Text View journal details

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Primary structure of wheat germ phenylalanine transfer RNA.

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