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PMID: 5253658 Published · ppublish English Journal Article

The cytoplasmic RNA of HeLa cells: new discrete species associated with mitochondria.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 62 ·No. 1 ·1969-01-00 ·Pages 218-25

Vesco C, Penman S

Abstract

Two new species of cytoplasmic RNA with approximate sedimentation values of 12S and 21S, and which appear associated with mitochondria, are described. The species are unmethylated, are relatively metabolically stable, and have a 43 per cent G + C content. Their synthesis is uniquely resistant to inhibition by UV irradiation. The 12S and 21S RNA do not appear to be components of polysome-like structures.

MeSH Terms
Electrophoresis Gels HeLa Cells In Vitro Techniques Mitochondria Potassium Isotopes RNA/analysis,isolation & purification
Chemicals
Gels Potassium Isotopes RNA
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Vesco C
Penman S
References (19)
19 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.62.1.218
Published
1969-01-00
Pages
218-25
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC285976
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.62.1.218 PMC Full Text View journal details
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