Studies on the control of pyrimidine biosynthesis in human diploid cell strains, I. Effect of 6-azauridine on cellular phenotype.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 57 ·No. 4 ·1967-04-00 ·Pages 925-32

Pinsky L, Krooth RS

Abstract

暂无摘要

MeSH Terms

Antimetabolites/pharmacology Carboxy-Lyases/metabolism Culture Techniques Glucosyltransferases/metabolism Humans Molecular Biology Mutation Nucleosides/pharmacology Pyrimidines/biosynthesis Uracil Nucleotides

Chemicals

Antimetabolites Nucleosides Pyrimidines Uracil Nucleotides Glucosyltransferases Carboxy-Lyases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Pinsky L

Krooth R S

References (16)

16 references, click to expand

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Orotidylic acid decarboxylase: inhibition studies with azauridine 5'-phosphate.
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Reversal of mutant phenotypes by 5-fluorouracil: an approach to nucleotide sequences in messenger-RNA.
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Pyrimidine metabolism in man. V. The measurement in vivo of the biochemical effect of antineoplastic agents in animal and human subjects.
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Studies on cell lines developed from the tissues of patients with galactosemia.
J Exp Med. 1961 Jun 1;113:1155-71 PMID: 13754521
PROPERTIES ODF DIPLOID CELL STRAINS DEVELOPED FROM PATIENTS WITH AN INHERITED ABNORMALITY OF URIDINE BIOSYNTHESIS.
Cold Spring Harb Symp Quant Biol. 1964;29:189-212 PMID: 14278466
HEREDITARY OROTIC ACIDURIA AND MEGALOBLASTIC ANAEMIA: A SECOND CASE, WITH RESPONSE TO URIDINE.
Br Med J. 1965 Feb 27;1(5434):547-52 PMID: 14243056
ERYTHROCYTE GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN CAUCASIANS: NEW INHERITED VARIANT.
Science. 1964 Sep 4;145(3636):1056-7 PMID: 14172618
Inheritance of an erythrocyte acetylesterase variant in man.
Am J Hum Genet. 1962 Sep;14:295-300 PMID: 13919743
PYRIMIDINE METABOLISM IN MAN. IV. THE ENZYMATIC DEFECT OF OROTIC ACIDURIA.
J Clin Invest. 1961 Apr;40(4):656-64 PMID: 16695858
Amino acid metabolism in mammalian cell cultures.
Science. 1959 Aug 21;130(3373):432-7 PMID: 13675766
Enzyme studies on diploid cell strains developed from patients with hereditary orotic aciduria.
Johns Hopkins Med J. 1967 Feb;120(2):81-8 PMID: 6021362
The biochemical activity of 6-azauridine: interference with pyrimidine metabolism in transplantable mouse tumors.
J Biol Chem. 1959 Nov;234:2992-7 PMID: 14430761
Protein measurement with the Folin phenol reagent.
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Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.57.4.925

Published

1967-04-00

Pages

925-32

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC224636

Subset

External Links

PubMed source DOI: 10.1073/pnas.57.4.925 PMC Full Text View journal details

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Studies on the control of pyrimidine biosynthesis in human diploid cell strains, I. Effect of 6-azauridine on cellular phenotype.

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