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PMID: 518922 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Interaction of alpha-actinin, filamin and tropomyosin with F-actin.

Biochimica et biophysica acta ·Vol. 581 ·No. 2 ·1979-12-14 ·Pages 365-70

Zeece MG, Robson RM, Bechtel PJ

Abstract

The abilities of alpha-actinin, filamin and tropomyosin to bind F-actin were examined by cosedimentation experiments. Results indicated that smooth muscle alpha-actinin and filamin can bind to actin filaments simultaneously with little evidence of competition. In contrast, tropomyosin exhibits marked competition with either filamin or alpha-actinin for sites on actin filaments.

MeSH Terms

Actinin Actins Animals Carrier Proteins Chickens Contractile Proteins Gizzard, Avian/analysis Macromolecular Substances Muscle Proteins Muscle, Smooth/analysis Protein Binding Tropomyosin Turkeys

Chemicals

Actins Carrier Proteins Contractile Proteins Macromolecular Substances Muscle Proteins Tropomyosin Actinin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Zeece M G

Robson R M

Bechtel P J

Article Info

Journal

Biochimica et biophysica acta

Abbr.

Biochim Biophys Acta

ISSN

0006-3002

DOI

10.1016/0005-2795(79)90258-7

Published

1979-12-14

Pages

365-70

Language

English

Region

Netherlands

NLM ID

0217513

Subset

External Links

PubMed source DOI: 10.1016/0005-2795(79)90258-7

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Interaction of alpha-actinin, filamin and tropomyosin with F-actin.

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