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PMID: 5055045 Published · ppublish English Journal Article

RNA metabolism in tracheal epithelium: alteration in hamsters deficient in vitamin A.

Science (New York, N.Y.) ·Vol. 177 ·No. 4054 ·1972-09-22 ·Pages 1105-8

Kaufman DG, Baker MS, Smith JM, Henderson WR, Harris CC, Sporn MB, Saffiotti U

Abstract

The electrophoretic pattern of RNA molecules that are synthesized in vitro in tracheal epithelium from hamsters deficient in vitamin A differs from that of RNA synthesized in normal, pair-fed control hamsters. There is less RNA of low electrophoretic mobility in the epithelial cells deficient in vitamin A. This alteration is reversed after the deficient animals have been treated with vitamin A.

MeSH Terms
Animals Cricetinae Electrophoresis Epithelium/metabolism In Vitro Techniques RNA/analysis,biosynthesis Trachea/analysis,metabolism Tritium Uridine/metabolism Vitamin A/therapeutic use Vitamin A Deficiency/drug therapy,metabolism
Chemicals
Tritium Vitamin A RNA Uridine
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Kaufman D G
Baker M S
Smith J M
Henderson W R
Harris C C
Sporn M B
Saffiotti U
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1972-09-22
Pages
1105-8
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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