Hemin control of globin synthesis: action of an inhibitor formed in the absence of hemin on the reticulocyte cell-free system and its reversal by a ribosomal factor.

Animals Blood Proteins/antagonists & inhibitors,biosynthesis,isolation & purification,pharmacology Carbon Isotopes Cell-Free System Centrifugation, Density Gradient Chemical Precipitation Chromatography, DEAE-Cellulose Chromatography, Ion Exchange Globins/biosynthesis Heme/pharmacology Histidine/metabolism Hydrogen-Ion Concentration Isoleucine/metabolism Kinetics Leucine/metabolism Potassium Chloride Rabbits Reticulocytes/cytology,drug effects,metabolism Ribosomes/drug effects,metabolism Trypsin

Blood Proteins Carbon Isotopes Isoleucine Heme Histidine Potassium Chloride Globins Trypsin Leucine