The effects of collagen and kaolin on the intrinsic coagulant activity of platelets. Evidence for an alternative pathway in intrinsic coagulation not requiring factor XII.

Blood Coagulation/drug effects Blood Coagulation Disorders/blood Blood Platelets/drug effects Collagen/pharmacology Factor IX Factor VIII Factor XI Factor XII Hemostasis Humans Kaolin/pharmacology Platelet Adhesiveness/drug effects

Kaolin Factor VIII Factor IX Factor XII Collagen Factor XI