Determination of blastoderm cells in Drosophila melanogaster.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 68 ·No. 9 ·1971-09-00 ·Pages 2217-21

Chan LN, Gehring W

Abstract

A method for culturing blastoderm cells of Drosophila in vivo has been developed that allows these cells to differentiate into larval or adult structures. By intermixture of genetically marked cells from bisected and whole embryos, it was shown that blastoderm cells are restricted in their potential for forming adult epidermal structures. Cells isolated from anterior-half embryos are determined for forming head and thoracic structures, whereas cells from posterior-half embryos are determined for forming thoracic and abdominal structures. The specificity of determination and the localization of determinative factors is discussed.

MeSH Terms

Animals Cell Differentiation Culture Techniques Drosophila melanogaster/anatomy & histology,cytology,growth & development Genotype Germ Layers/cytology Larva Morphogenesis

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Chan L N

Gehring W

References (15)

15 references, click to expand

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Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.68.9.2217

Published

1971-09-00

Pages

2217-21

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC389388

Subset

External Links

PubMed source DOI: 10.1073/pnas.68.9.2217 PMC Full Text View journal details

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Determination of blastoderm cells in Drosophila melanogaster.

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