Genetic map of bacteriophage alpha.

Journal of virology ·Vol. 6 ·No. 1 ·1970-07-00 ·Pages 49-57

Kejzlarovà J, Donini P, Eremenko-Volpe T, Graziosi F

Abstract

Temperature-sensitive mutants of phage alpha were obtained by means of various mutagens and assigned to 25 complementation groups. Temperature-sensitive mutants belonging to 21 complementation groups and a mutant giving turbid plaques were used to perform two- and three-factor crosses. Seventeen of the cistrons and the turbid mutant were shown to belong to the same linear linkage group, which showed no signs of circularity. The remaining four unlinked cistrons showed peculiarities in their recombination properties. Genes which are known to be expressed earlier apear to be grouped together in a terminal segment of the linkage group.

MeSH Terms

Bacillus megaterium Bacteriophages/drug effects,growth & development,isolation & purification,radiation effects Chromosome Mapping Crosses, Genetic Genetic Complementation Test Genetics, Microbial Guanidines/pharmacology Hydroxylamines/pharmacology Methane/pharmacology Mutagens Mutation Nitrites/pharmacology Nitroso Compounds/pharmacology Recombination, Genetic Spectrophotometry Sulfonic Acids/pharmacology Temperature Ultraviolet Rays

Chemicals

Guanidines Hydroxylamines Mutagens Nitrites Nitroso Compounds Sulfonic Acids Methane

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Kejzlarovà J

Donini P

Eremenko-Volpe T

Graziosi F

References (15)

15 references, click to expand

TEMPERATURE-SENSITIVE MUTANTS OF BACTERIOPHAGE T4D: THEIR ISOLATION AND GENETIC CHARACTERIZATION.
Genetics. 1964 Apr;49:649-62 PMID: 14156925
Gene order in prophage P22.
Virology. 1965 Oct;27(2):229-31 PMID: 5840894
Segregants from lysogenic heterogenotes carrying recombinant lambda prophages.
Virology. 1963 Jun;20:344-56 PMID: 14018106
MAPPING OF TEMPERATURE-SENSITIVE MUTANTS IN BACTERIOPHAGE T5.
Genetics. 1965 Jan;51:157-66 PMID: 14258069
SENSITIVITY TO X-RAYS AND ULTRAVIOLET LIGHT OF INTRACELLULAR PHAGE ALPHA.
Virology. 1965 Jun;26:359-67 PMID: 14324000
A genetic study of temperature-sensitive mutants of the subtilis phage SP82.
Virology. 1966 Dec;30(4):650-60 PMID: 4959194
Variations in genetic recombination due to amber mutations in T4D bacteriophage.
J Virol. 1969 Feb;3(2):171-5 PMID: 4886654
CHROMATOGRAPHIC PURIFICATION OF ONE OF THE COMPLEMENTARY STRANDS OF DNA OF PHAGE A.
Biochim Biophys Acta. 1964 Mar 23;80:514-6 PMID: 14153857
GENETIC RECOMBINATION BETWEEN LAMBDA PROPHAGE AND IRRADIATED LAMBDA DG PHAGE.
Virology. 1964 Jun;23:234-51 PMID: 14187911
[Adenosine and antagonism of the action of theophylline in Bacillus megatherium].
Riv Ist Sieroter Ital. 1957 Mar-Apr;32(2):128-37 PMID: 13454579
Repair and recombination in phage T4. I. Genes affecting recombination.
Cold Spring Harb Symp Quant Biol. 1968;33:325-31 PMID: 4891972
Chronology of viral functions in bacteriophage alpha.
J Virol. 1967 Aug;1(4):717-22 PMID: 4987172
Sensitive mutants of bacteriophage lambda.
Virology. 1961 May;14:22-32 PMID: 13690195
EFFECT OF ACRIDINES AND TEMPERATURE ON A STRAIN OF BACILLUS MEGATERIUM LYSOGENIC FOR PHAGE ALPHA.
Virology. 1965 Apr;25:643-9 PMID: 14329137
A COMPARATIVE GENETIC STUDY OF CONDITIONAL LETHAL MUTATIONS OF BACTERIOPHAGE T4D.
Genetics. 1964 Apr;49:635-48 PMID: 14156924

Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.6.1.49-57.1970

Published

1970-07-00

Pages

49-57

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC376089

Subset

External Links

PubMed source DOI: 10.1128/JVI.6.1.49-57.1970 PMC Full Text View journal details

Analysis Services

Genetic map of bacteriophage alpha.

Contact

WeChat Official Account