Transmissible mink encephalopathy: experimental transmission to the squirrel monkey.

Science (New York, N.Y.) ·Vol. 169 ·No. 3950 ·1970-09-11 ·Pages 1088-90

Eckroade RJ, Zu Rhein GM, Marsh RF, Hanson RP

Abstract

A progressive, fatal spongiform encephalopathy developed in three squirrel monkeys 11 months after inoculation with primate-passaged transmissible mink encephalopathy agent. The clinical symptoms and histopathologic and electron microscopic findings suggest that this naturally occurring disease of mink has been transmitted experimentally to squirrel monkeys.

MeSH Terms

Animals Apraxias Ataxia Blood Protein Disorders/veterinary Brain Diseases/etiology,pathology,veterinary Cerebral Cortex/pathology Female Haplorhini Humans Microscopy, Electron Mink Monkey Diseases/etiology,pathology Spinal Cord/pathology Tremor Virus Diseases/pathology,veterinary

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Eckroade R J

Zu Rhein G M

Marsh R F

Hanson R P

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.169.3950.1088

Published

1970-09-11

Pages

1088-90

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.169.3950.1088 View journal details

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Transmissible mink encephalopathy: experimental transmission to the squirrel monkey.

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