[8-Arginine]-vasopressinoic acid: an inhibitor of rabbit kidney adenyl cyclase.

Science (New York, N.Y.) ·Vol. 167 ·No. 3921 ·1970-02-20 ·Pages 1134-5

Dousa T, Hechter O, Walter R, Schwartz IL

Abstract

Neurohypophyseal hormnones and several synthetic analogs stimulate adenyl cyclase prepared from rabbit kidney medullary tissue. [8-Arginine]-vasopressinoic acid inhibits the stimulation of medullary adenyl cyclase by neurohypophyseal peptides but does not influence the action of parathyroid hormone on adenyl cyclase from kidiney cortex.

MeSH Terms

Adenylyl Cyclase Inhibitors Animals Arginine/pharmacology Enzyme Inhibitors Kidney/enzymology Models, Chemical Parathyroid Hormone/antagonists & inhibitors Rabbits Vasopressins/chemical synthesis,pharmacology

Chemicals

Adenylyl Cyclase Inhibitors Enzyme Inhibitors Parathyroid Hormone Vasopressins Arginine

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Dousa T

Hechter O

Walter R

Schwartz I L

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.167.3921.1134

Published

1970-02-20

Pages

1134-5

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.167.3921.1134 View journal details

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[8-Arginine]-vasopressinoic acid: an inhibitor of rabbit kidney adenyl cyclase.

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