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PMID: 4975752 Published · ppublish English Journal Article

Antimetabolite action of 5-methyltryptophan in Bacillus subtilis.

Journal of bacteriology ·Vol. 97 ·No. 3 ·1969-03-00 ·Pages 1500-1

Jensen RA

Abstract

The roles of anthranilate and histidine in the regulation of tryptophan synthesis were implicated by observations of antagonistic relationships with 5-methyltryptophan in Bacillus subtilis.

MeSH Terms
Bacillus subtilis/drug effects,growth & development Histidine/pharmacology Indoles/pharmacology Tryptophan/biosynthesis,pharmacology ortho-Aminobenzoates/pharmacology
Chemicals
Indoles ortho-Aminobenzoates Histidine Tryptophan
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Jensen R A
References (5)
5 references, click to expand
  1. THE REGULATORY SIGNIFICANCE OF INTERMEDIARY METABOLITES: CONTROL OF AROMATIC ACID BIOSYNTHESIS BY FEEDBACK INHIBITION IN BACILLUS SUBTILIS.
    J Mol Biol. 1965 Jun;12:468-81 PMID: 14337509
  2. Characterization of mutants with single and multiple defects in the tryptophan biosynthetic pathway in Bacillus subtilis.
    J Bacteriol. 1968 Oct;96(4):1273-80 PMID: 4971887
  3. Gene Linkage in DNA Transfer: A Cluster of Genes Concerned with Aromatic Biosynthesis in Bacillus Subtilis.
    Genetics. 1963 Apr;48(4):529-51 PMID: 17248161
  4. False feedback inhibition: inhibition of tryptophan biosynthesis by 5-methyltryptophan.
    J Biol Chem. 1960 Apr;235:1098-102 PMID: 14424820
  5. The partial purification and properties of indole-3-glycerol phosphate synthetase from Escherichia coli.
    Biochim Biophys Acta. 1960 Oct 7;43:489-500 PMID: 13705110
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
Published
1969-03-00
Pages
1500-1
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC249876
Subset
IM
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