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PMID: 4973125 Published · ppublish English Journal Article

Genetic control of the beta-ketoadipate pathway in Pseudomonas aeruginosa.

Journal of bacteriology ·Vol. 96 ·No. 5 ·1968-11-00 ·Pages 1488-99

Kemp MB, Hegeman GD

Abstract

The regulation and genetic control of the beta-ketoadipate pathway in Pseudomonas aeruginosa were investigated. The pattern of enzyme induction is apparently the same as in P. putida. Mutants were obtained for all but 1 of the 11 structural genes; the proximity of these genes on the chromosome was examined by transduction of the mutants with phage F116. If a group of enzymes was induced by the same compounds, the corresponding genes were closely clustered. Surprisingly, some locispecifying enzymes not sharing a common inducer were also clustered. It is suggested that this latter finding may indicate a degree of chromosomal specialization.

MeSH Terms
Adipates/metabolism Bacteriophages Catechols Chromosome Mapping Chromosomes, Bacterial Esterases/metabolism Genes Genetics, Microbial Isomerases/metabolism Keto Acids Molecular Biology Mutation Oxygen Consumption Oxygenases/metabolism Pseudomonas aeruginosa/enzymology Transduction, Genetic Transferases/metabolism
Chemicals
Adipates Catechols Keto Acids Oxygenases Transferases Esterases Isomerases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kemp M B
Hegeman G D
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30 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.96.5.1488-1499.1968
Published
1968-11-00
Pages
1488-99
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC315200
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.96.5.1488-1499.1968 PMC Full Text View journal details
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