Neuromuscular blocking properties of stereoisomeric androstane-3,l7-bisquaternary ammonium salts.

British journal of pharmacology and chemotherapy ·Vol. 30 ·No. 1 ·1967-05-00 ·Pages 194-202

Bamford DG, Biggs DF, Davis M, Parnell EW

Abstract

暂无摘要

MeSH Terms

Animals Cats Chloralose/pharmacology Curare/pharmacology Female Gallamine Triethiodide/pharmacology Haplorhini Male Muscles/drug effects Pentobarbital/pharmacology Quaternary Ammonium Compounds/pharmacology Sciatic Nerve/drug effects Steroids/pharmacology Succinylcholine/pharmacology Thiopental/pharmacology Tubocurarine/pharmacology

Chemicals

Quaternary Ammonium Compounds Steroids Chloralose Curare Pentobarbital Succinylcholine Thiopental Gallamine Triethiodide Tubocurarine

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Bamford D G

Biggs D F

Davis M

Parnell E W

References (13)

13 references, click to expand

The pharmacological actions of polymethylene bistrimethyl-ammonium salts.
Br J Pharmacol Chemother. 1949 Dec;4(4):381-400 PMID: 15398551
Chemical nature and pharmacological actions of quaternary ammonium salts.
Fortschr Arzneimittelforsch. 1960;2:135-226 PMID: 13691732
RELAXANT ACTION IN MAN OF DIPYRANDIUM CHLORIDE (M&B 9105A). (A STEROID BIS-QUATERNARY AMMONIUM SALT).
Br J Anaesth. 1964 Dec;36:761-8 PMID: 14247458
Structural studies of hexa-methonium bromides, (CH3)3N(CH2)nN(CH3)3.2Br. 2H2O, in relation to their pharmacological action.
Acta Crystallogr. 1965 Nov 10;19(5):827-40 PMID: 5897691
NON-DEPOLARISING NEUROMUSCULAR BLOCKADE BY 3-ALPHA,17-ALPHA-BIS(QUATERNARY AMMONIUM) 5-ALPHA-ANDROSTANES.
J Pharm Pharmacol. 1965 Jan;17:55-8 PMID: 14285698
Muscle-relaxant properties of a steroid bis-quaternary ammonium salt.
Experientia. 1964 Mar 15;20(3):119-20 PMID: 4955010
SOME CHEMICAL ASPECTS OF NEUROMUSCULAR BLOCK.
Prog Med Chem. 1963;19:1-51 PMID: 14146301
Biological activity in steroids possessing nitrogen atoms. I. Synthetic nitrogenous steroids.
J Pharm Pharmacol. 1962 Jun;14:325-49 PMID: 13860020
[CURARIZING ACTIVITY OF 3-BETA,20-ALPHA-BISTRIMETHYLAMMONIUM-5-ALPHA-PREGNANE DICHLORIDE (MALOUETINE) AND OF ITS STEREOISOMERS].
Arch Int Pharmacodyn Ther. 1964 Jan 1;147:209-19 PMID: 14116930
[On the toxicity and curarizing power of amalouetine chloride].
Ann Pharm Fr. 1960 Sep;18:678-80 PMID: 13738687
Steric aspects of drug action.
Biochem Soc Symp. 1960;19:46-66 PMID: 13687055
Equidistance concept and structure-activity relationship of curarizing drugs.
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1952;214(2):214-26 PMID: 14953228
Inter-quaternary distance and ganglion-blocking activity in bis-quaternary compounds.
Proc R Soc Lond B Biol Sci. 1959 Apr 21;150(940):381-402 PMID: 13645637

Article Info

Journal

British journal of pharmacology and chemotherapy

Abbr.

Br J Pharmacol Chemother

ISSN

0366-0826

DOI

10.1111/j.1476-5381.1967.tb02125.x

Published

1967-05-00

Pages

194-202

Language

English

Region

England

NLM ID

0154627

PMCID

PMC1557233

Subset

External Links

PubMed source DOI: 10.1111/j.1476-5381.1967.tb02125.x PMC Full Text

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Neuromuscular blocking properties of stereoisomeric androstane-3,l7-bisquaternary ammonium salts.

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