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PMID: 4943631 Published · ppublish ger Journal Article Review

[Pathogenesis of alcohol-induced fat incorporation into the liver].

Zur Pathogenese der durch Alkohol induzierten Fetteinlagerung in die Leber.

Klinische Wochenschrift ·Vol. 49 ·No. 22 ·1971-11-15 ·Pages 1201-9

Bode C, Goebell H

Abstract

暂无摘要

MeSH Terms
Adipose Tissue/metabolism Alcohol Oxidoreductases/metabolism Animals Carboxy-Lyases/pharmacology Coenzyme A/metabolism Cytoplasm/drug effects Ethanol/pharmacology,toxicity Fatty Acids/biosynthesis,metabolism Fatty Liver/chemically induced,enzymology,metabolism Glycerophosphates/analysis,metabolism Humans Hyperthyroidism Ketone Bodies/biosynthesis Liver/drug effects Mitochondria, Liver/drug effects Oxidation-Reduction Protein Deficiency/metabolism Rats Triglycerides/metabolism
Chemicals
Fatty Acids Glycerophosphates Ketone Bodies Triglycerides Ethanol Alcohol Oxidoreductases Carboxy-Lyases Coenzyme A
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Bode C
Goebell H
References (51)
51 references, click to expand
  1. The rate of ethanol metabolism in fed and fasting animals.
    J Biol Chem. 1959 Jun;234(6):1544-9 PMID: 13654414
  2. Effect of beta-hydroxybutyrate on lipid mobilization.
    Am J Physiol. 1967 Mar;212(3):683-7 PMID: 6021051
  3. ALCOHOL HYPOGLYCEMIA. I. CARBOHYDRATE METABOLISM OF PATIENTS WITH CLINICAL ALCOHOL HYPOGLYCEMIA AND THE EXPERIMENTAL REPRODUCTION OF THE SYNDROME WITH PURE ETHANOL.
    J Clin Invest. 1963 Jul;42(7):1112-33 PMID: 16695908
  4. The effect of ethanol on fatty acid metabolism; stimulation of hepatic fatty acid synthesis in vitro.
    J Clin Invest. 1961 Feb;40:394-9 PMID: 13761991
  5. Metabolic derangement induced by alcohol.
    Annu Rev Med. 1967;18:35-54 PMID: 5337531
  6. ELEVATION OF LONG CHAIN ACYL COA DERIVATIVES IN LIVERS OF FASTED RATS.
    Biochem Z. 1963 Sep 19;339:77-82 PMID: 14092451
  7. Effect of acute ethanol intoxication on liver and plasma lipid fractions of the rat.
    Am J Physiol. 1958 Sep;194(3):453-6 PMID: 13571406
  8. Alcoholic fatty liver in man on a high protein and low fat diet.
    Am J Med. 1968 Feb;44(2):200-6 PMID: 5635674
  9. THE INHIBITION OF ACETYL COA CARBOXYLASE BY LONG CHAIN ACYL COA DERIVATIVES.
    Biochem Z. 1963 Aug 14;337:505-9 PMID: 14042693
  10. [The fatty liver and its problems].
    Internist (Berl). 1966 Jan;7(1):21-7 PMID: 4862424
  11. EFFECT OF PROLONGED ETHANOL INGESTION ON THE TRANSPORT AND METABOLISM OF LIPIDS IN MAN.
    N Engl J Med. 1965 Mar 25;272:610-5 PMID: 14255335
  12. METABOLIC EFFECTS OF ALCOHOL ON THE LIVER.
    N Engl J Med. 1964 Feb 13;270:351-6 CONTD PMID: 14085592
  13. Peripheral circulatory and metabolic consequences of thyrotoxicosis. II. Uptake of free fatty acids by the gracilis muscle in normal and thyrotoxic dogs.
    Scand J Clin Lab Invest. 1967;19(1):15-28 PMID: 6031315
  14. Effects of ethanol on free coenzyme A, free carnitine and their fatty acid esters in rat liver.
    Biochim Biophys Acta. 1970 Sep 8;210(3):448-55 PMID: 5471661
  15. Enhanced oxidation of alpha-glycerophosphate by mitochondria of thyroid-fed rats.
    J Biol Chem. 1959 Nov;234:3051-4 PMID: 14415220
  16. Plasma nonesterified fatty acids in hyperthyroid states.
    J Clin Invest. 1959 Feb;38(2):275-8 PMID: 13631057
  17. Studies on the pathogenesis of the ethanol-induced fatty liver. I. Synthesis and oxidation of fatty acids by the liver.
    J Clin Invest. 1961 Aug;40:1355-62 PMID: 13740121
  18. STUDIES ON THE PATHOGENESIS OF THE ETHANOL-INDUCED FATTY LIVER. II. EFFECT OF ETHANOL ON PALMITATE-1-C-14 METABOLISM BY THE ISOLATED PERFUSED RAT LIVER.
    J Clin Invest. 1964 Jul;43:1338-47 PMID: 14192514
  19. [On disorders of fatty acid synthesis in hunger and alloxan diabetes. I. Fatty acid synthesis in the liver of normal and fasting rats].
    Biochem Z. 1961;334:203-17 PMID: 13729884
  20. Ethanol-induced changes in hepatic alpha-glycerophosphate and triglyceride concentrations in normal and thyroxine-treated rats.
    Metabolism. 1970 Dec;19(12):1036-45 PMID: 5492042
  21. The influence of beta-adrenergic blockade on the ethanol-induced derangement of lipid transport.
    Arch Int Pharmacodyn Ther. 1967 Apr;166(2):333-41 PMID: 6032957
  22. [Oxidation of ethyl alcohol in the isolated liver and in the isolated hind body of the rat].
    Hoppe Seylers Z Physiol Chem. 1960 Feb 22;318:1-5 PMID: 13824016
  23. Effects of adrenergic blockade and nicotinic acid on the mobilization of free fatty acids.
    Life Sci. 1965 Jun;4(11):1115-24 PMID: 4284522
  24. Influence of ethanol on the metabolism of perfused normal, fatty and cirrhotic rat livers.
    Biochem J. 1966 Sep;100(3):768-78 PMID: 5969289
  25. On the pathogenesis of ethanol-induced lipid accumulation in the liver. II. Effect of stimulation of the -glycerophosphate cycle on metabolic changes in the liver caused by ethanol.
    Horm Metab Res. 1970 Sep;2(5):282-6 PMID: 5524675
  26. Role of hypophysis and adrenals in fatty infiltration of liver resulting from acute ethanol intoxication.
    Am J Physiol. 1956 Jan;184(1):29-34 PMID: 13283085
  27. Effect of ethanol intoxication on plasma free fatty acids in the rat.
    Q J Stud Alcohol. 1961 Jun;22:250-3 PMID: 13765884
  28. [Alcohol oxidation and acetoacetate formation in normal and glycogendeficient intact rat liver].
    Hoppe Seylers Z Physiol Chem. 1958;312(4-6):243-8 PMID: 13620210
  29. Changes in the level of the fatty acid synthesizing enzymes during starvation.
    Biochim Biophys Acta. 1962 Apr 9;58:354-6 PMID: 14458379
  30. [The influence of a protracted ethyl alcohol load on catecholamine excretion in the rat urine].
    Helv Med Acta. 1961 Mar;28:89-98 PMID: 13783252
  31. THE EFFECT OF INFUSIONS ON ETHANOL ON THE PLASMA FREE FATTY ACIDS IN MAN.
    Clin Sci. 1964 Feb;26:47-54 PMID: 14117059
  32. [Short-term effect of ethyl alcohol on serum lipids of healthy fasting persons].
    Z Gesamte Exp Med. 1970;152(3):187-200 PMID: 5505948
  33. Variations in tissue contents of coenzyme A thio esters and possible metabolic implications.
    Biochem J. 1964 Dec;93(3):550-7 PMID: 5839190
  34. The effects of palmitylcarnitine on hepatic fatty acid synthesis and on acetyl CoA carboxylase activity.
    Biochem Biophys Res Commun. 1966 Mar 22;22(6):737-43 PMID: 5944773
  35. Localization of the block in lipogenesis resulting from feeding fat.
    J Biol Chem. 1963 Apr;238:1266-72 PMID: 14014122
  36. A sensitive enzymic assay for carnitine.
    Biochem J. 1964 Apr;91(1):2C-4C PMID: 5833385
  37. Metabolic effects of ethanol in perfused rat liver.
    J Biol Chem. 1969 Sep 25;244(18):5044-54 PMID: 4390471
  38. [On the metabolite content and the metabolite concentration in the liver of the rat].
    Biochem Z. 1959;332:18-46 PMID: 14402528
  39. [ON INHIBITION OF LIPID SYNTHESIS IN THE LIVER IN DIABETES].
    Biochem Z. 1963 Jul 10;337:349-59 PMID: 14046119
  40. Ethanol metabolism and production of free acetate in the human liver.
    J Clin Invest. 1962 May;41:955-61 PMID: 14467395
  41. [Hydrogen pathway in mitochondria. I. Hydrogen transfer from succinate to acetoacetate].
    Biochem Z. 1963;337:120-45 PMID: 14033543
  42. INFLUENCE OF ETHANOL ON THE LIVER METABOLISM OF FED AND STARVED RATS.
    Biochem J. 1965 Jan;94:259-65 PMID: 14342239
  43. ROLE OF HEPATIC L-ALPHA-GLYCEROPHOSPHATE AND TRIGLYCERIDE SYNTHESIS IN PRODUCTION OF FATTY LIVER BY ETHANOL.
    Proc Soc Exp Biol Med. 1963 Aug-Sep;113:814-7 PMID: 14078608
  44. [Pathogenesis of fat accumulation in the liver by alcohol. 3. Effect of ethanol on metabolites and coenzymes of energy supplying metabolism in the liver and blood at standard diet and low protein diet].
    Klin Wochenschr. 1970 Oct 1;48(19):1180-8 PMID: 4394713
  45. [ALDEHYDE- AND ALCOHOL DEHYDROGENASE ACTIVITIES IN THE LIVER AND KIDNEY OF RATS].
    Biochem Z. 1965 Feb 24;341:300-14 PMID: 14267689
  46. Alcohol-induced hepatic injury in nonalcoholic volunteers.
    N Engl J Med. 1968 Apr 18;278(16):869-76 PMID: 5641156
  47. Depot fat as source of increased liver triglycerides after ethanol.
    Biochem Biophys Res Commun. 1960 Dec;3:635-40 PMID: 13715909
  48. Effect of chronic ethanol intoxication on liver lipid content of rats.
    Proc Soc Exp Biol Med. 1955 Feb;88(2):246-9 PMID: 14357404
  49. [Changes in alcohol dehydrogenase activity in rat liver following protein deficiency and ethanol].
    Z Gesamte Exp Med. 1970;152(2):111-24 PMID: 5516373
  50. The effect of acute ethanol intoxication on chloroform-induced liver damage.
    J Pharmacol Exp Ther. 1962 Feb;135:245-51 PMID: 14460945
  51. PATHOGENESIS OF ETHANOL-INDUCED FATTY LIVER. 3. IN VIVO AND VITRO EFFECTS OF ETHANOL ON HEPATIC FATTY ACID METABOLISM IN RATS.
    J Lipid Res. 1965 Apr;6:269-77 PMID: 14330769
Article Info
Journal
Klinische Wochenschrift
Abbr.
Klin Wochenschr
ISSN
0023-2173
DOI
10.1007/BF01732728
Published
1971-11-15
Pages
1201-9
Language
ger
Region
Germany
NLM ID
2985205R
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01732728
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