Effect of rifampin on the development of ribonucleic acid bacteriophage Q .

Journal of virology ·Vol. 8 ·No. 3 ·1971-09-00 ·Pages 286-92

Passent J, Kaesberg P

Abstract

The drug rifampin, when added at the time of infection, inhibits synthesis of the phage Qbeta. Both viral ribonucleic acids and viral proteins are made in nearly the same amount as in the absence of rifampin, but the rate of assembly into phage particles is low.

MeSH Terms

Antigen-Antibody Complex Carbon Isotopes Coliphages/drug effects,growth & development,immunology,metabolism Drug Resistance, Microbial Electrophoresis, Disc Escherichia coli/drug effects,immunology Genetics, Microbial Lysine/metabolism Mutation RNA, Viral/biosynthesis Rifampin/pharmacology Time Factors Tritium Uracil/metabolism Viral Proteins/biosynthesis

Chemicals

Antigen-Antibody Complex Carbon Isotopes RNA, Viral Viral Proteins Tritium Uracil Lysine Rifampin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Passent J

Kaesberg P

References (18)

18 references, click to expand

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Nature. 1969 Apr 19;222(5190):273-4 PMID: 4305117
Rifampicin inhibits the growth of some mammalian viruses.
Nature. 1969 Apr 26;222(5191):341-5 PMID: 5782109
Comparative antigenicities of Q beta phage, its structural components and reconstituted particles.
Virology. 1969 Aug;38(4):703-6 PMID: 5803949
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J Mol Biol. 1969 Dec 14;46(2):349-53 PMID: 4902520
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Proc Natl Acad Sci U S A. 1970 Jul;66(3):677-84 PMID: 5269234
Subunit structure of Q-beta replicase.
Nature. 1970 Nov 7;228(5271):525-7 PMID: 5472467
Characterization of the subunits of Q-beta replicase.
Nature. 1970 Nov 7;228(5271):527-33 PMID: 5472468
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Virology. 1970 Oct;42(2):401-14 PMID: 4923013
Acrylamide gel electrophoresis of bacteriophage Q beta: electrophoresis of the intact virions and of the viral proteins.
Virology. 1970 Oct;42(2):437-52 PMID: 5489225
Characterization of the initial peptide of Q-beta RNA polymerase and control of its synthesis.
Proc Natl Acad Sci U S A. 1971 Feb;68(2):276-9 PMID: 5277068
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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.8.3.286-292.1971

Published

1971-09-00

Pages

286-92

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC356241

Subset

External Links

PubMed source DOI: 10.1128/JVI.8.3.286-292.1971 PMC Full Text View journal details

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Effect of rifampin on the development of ribonucleic acid bacteriophage Q .

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