Scopafungin, a crystalline antibiotic produced by Streptomyces hygroscopicus var. enhygrus var. nova.

Applied microbiology ·Vol. 22 ·No. 3 ·1971-09-00 ·Pages 303-8

Johnson LE, Dietz A

Abstract

Scopafungin (U-29,479) is a crystalline, nonpolyenic antimicrobial agent obtained from the culture broth of Streptomyces hygroscopicus var. enhygrus var. nova UC-2397. Scopafungin inhibits, in vitro, a variety of pathogenic fungi, yeasts, and gram-positive bacteria.

MeSH Terms

Anti-Bacterial Agents/biosynthesis,pharmacology Antifungal Agents/biosynthesis,pharmacology Bacteria/drug effects Bacteriological Techniques Chromatography, Paper Fermentation Fungi/drug effects Lactones Species Specificity Streptomyces/classification,growth & development,metabolism

Chemicals

Anti-Bacterial Agents Antifungal Agents Lactones scopafungin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Johnson L E

Dietz A

References (7)

7 references, click to expand

Taxonomy by carbon replication. II. Examination of eight additional cultures of Streptomyces hygroscopicus.
Appl Microbiol. 1968 Jun;16(6):935-41 PMID: 4874456
Streptomyces steffisburgensis sp.n.
J Bacteriol. 1967 Dec;94(6):2022-6 PMID: 6074404
The Utilization of Carbon Compounds by Some Actinomycetales as an Aid for Species Determination.
J Bacteriol. 1948 Jul;56(1):107-14 PMID: 16561537
The Production, Assay, and Antibiotic Activity of Actidione, an Antiobiotic from Streptomyces griseus.
J Bacteriol. 1948 Sep;56(3):283-91 PMID: 16561572
Taxonomy by carbon replication. I. An examination of Streptomyces hygroscopicus.
Appl Microbiol. 1962 May;10:258-63 PMID: 13886326
A broadened concept of the characteristics of Streptomyces hygroscopicus.
Appl Microbiol. 1956 Sep;4(5):243-50 PMID: 13363385
System of color wheels for streptomycete taxonomy.
Appl Microbiol. 1963 Jul;11:335-8 PMID: 13994094

Article Info

Journal

Applied microbiology

Abbr.

Appl Microbiol

ISSN

0003-6919

DOI

10.1128/am.22.3.303-308.1971

Published

1971-09-00

Pages

303-8

Language

English

Region

United States

NLM ID

7605802

PMCID

PMC376304

Subset

External Links

PubMed source DOI: 10.1128/am.22.3.303-308.1971 PMC Full Text

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Scopafungin, a crystalline antibiotic produced by Streptomyces hygroscopicus var. enhygrus var. nova.

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