Home LiteratureArticle Details

PMID: 493962 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Water, protein folding, and the genetic code.

Science (New York, N.Y.) ·Vol. 206 ·No. 4418 ·1979-11-02 ·Pages 575-7

Wolfenden RV, Cullis PM, Southgate CC

Abstract

The absolute affinities of amino acid side chains for solvent water closely match their relative distributions between the surface and the interior of native proteins and are associated with a remarkable bias in the genetic code.

MeSH Terms

Amino Acids/genetics Genetic Code Mutation Protein Conformation Solubility Thermodynamics Water

Chemicals

Amino Acids Water

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Wolfenden R V

Cullis P M

Southgate C C

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.493962

Published

1979-11-02

Pages

575-7

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.493962 View journal details

Analysis Services

Water, protein folding, and the genetic code.

Contact

WeChat Official Account