Home LiteratureArticle Details
PMID: 4937782 Published · ppublish English Journal Article

Location and orientation of the phoA locus on the Escherichia coli K-12 linkage map.

Journal of bacteriology ·Vol. 107 ·No. 3 ·1971-09-00 ·Pages 683-9

Nakata A, Peterson GR, Brooks EL, Rothman FG

Abstract

The order of gene loci in the phoA-phoR region of the Escherichia coli K-12 linkage map was demonstrated to be lac phoA proC phoR. The end of the phoA locus corresponding to the amino terminus of alkaline phosphatase was shown to be the end nearer proC. Translation (and transcription) of phoA is therefore in the anticlockwise direction relative to the conventional E. coli linkage map.

MeSH Terms
Alkaline Phosphatase/biosynthesis Chromosome Mapping Coliphages Conjugation, Genetic Crosses, Genetic Culture Media Escherichia coli/enzymology,growth & development Genes, Regulator Genetic Code Mutation Phenotype Recombination, Genetic Transduction, Genetic
Chemicals
Culture Media Alkaline Phosphatase
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Nakata A
Peterson G R
Brooks E L
Rothman F G
References (47)
47 references, click to expand
  1. Hybrid protein formation of E. coli alkaline phosphatase leading to in vitro complementation.
    J Mol Biol. 1963 Jul;7:1-12 PMID: 13991836
  2. Regulation of the biosynthesis of guanosine 5'-monophosphate: evidence for one operon.
    J Mol Biol. 1968 Jul 14;35(1):103-9 PMID: 4939774
  3. Current linkage map of Escherichia coli.
    Bacteriol Rev. 1970 Jun;34(2):155-75 PMID: 4918631
  4. Regulation of the enzymes of the tryptophan pathway in Escherichia coli.
    Genetics. 1965 Dec;52(6):1303-16 PMID: 5327408
  5. Divergent orientation of transcription from the biotin locus of Escherichia coli.
    J Mol Biol. 1971 Feb 28;56(1):53-62 PMID: 4929887
  6. Information transfer in Salmonella typhimurium.
    Proc Natl Acad Sci U S A. 1965 Jun;53(6):1335-40 PMID: 5324617
  7. REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF ISOLEUCINE AND VALINE. 3. MAP ORDER OF THE STRUCTURAL GENES AND OPERATOR GENES.
    J Bacteriol. 1965 Mar;89:661-4 PMID: 14273641
  8. Sense and nonsense in the genetic code. Three exceptional triplets can serve as both chain-terminating signals and amino acid codons.
    Science. 1968 Apr 12;160(3824):149-59 PMID: 4868223
  9. ON THE COLINEARITY OF GENE STRUCTURE AND PROTEIN STRUCTURE.
    Proc Natl Acad Sci U S A. 1964 Feb;51:266-72 PMID: 14124325
  10. Nonsense mutations in the maltose A region of the genetic map of Escherichia coli.
    J Bacteriol. 1969 Dec;100(3):1311-5 PMID: 4902812
  11. [REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF THE ENZYMES OF GALACTOSE METABOLISM IN ESCHERICHIA COLI K 12. II. THE GENETIC DETERMINISM OF THE REGULATION].
    J Mol Biol. 1963 Aug;7:183-205 PMID: 14062651
  12. Orientation of transcription of the lac operon and its repressor gene in Escherichia coli.
    J Mol Biol. 1969 Feb 28;40(1):145-51 PMID: 4903358
  13. Genetic control of repression of alkaline phosphatase in E. coli.
    J Mol Biol. 1961 Aug;3:425-38 PMID: 13725581
  14. Miscoding caused by 5-fluorouracil.
    J Mol Biol. 1969 Sep 14;44(2):363-75 PMID: 4940922
  15. REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF ISOLEUCINE AND VALINE. II. IDENTIFICATION OF TWO OPERATOR GENES.
    J Bacteriol. 1965 Mar;89:654-60 PMID: 14273640
  16. Revised linkage map of Escherichia coli.
    Bacteriol Rev. 1967 Dec;31(4):332-53 PMID: 4865540
  17. NATURE OF ETHYL METHANESULFONATE INDUCED REVERSIONS OF LAC-MUTANTS OF ESCHERICHIA COLI.
    Genetics. 1963 Oct;48:1357-75 PMID: 14071756
  18. Further genetic mapping of the phoA-phoR region for alkaline phosphatase synthesis in Escherichia coli K 12.
    Mol Gen Genet. 1970;109(1):18-26 PMID: 4922680
  19. Genetic mapping of regulator gene phoS for alkaline phosphatase in Escherichia coli.
    J Bacteriol. 1968 Mar;95(3):1182-3 PMID: 4868357
  20. Transduction by bacteriophage P-1 and the properties of the lac genetic region in E. coli and S. dysenteriae.
    Virology. 1961 Nov;15:299-311 PMID: 13894683
  21. The L-rhamnose genetic system in Escherichia coli K-12.
    Genetics. 1967 Mar;55(3):557-68 PMID: 5341476
  22. Direction of transcription of a regulatory gene in E. coli.
    Nature. 1968 Dec 28;220(5174):1287-90 PMID: 4882916
  23. Mapping of the galactose genes of Escherichia coli by transduction with phage P1.
    Virology. 1963 Feb;19:117-26 PMID: 14011089
  24. [A STRUCTURAL GENE-COMPLEX FOR THE PYRUVATE DEHYDROGENASE COMPLEX OF ESCHERICHIA COLI K-12].
    Z Vererbungsl. 1964 Nov 11;95:260-75 PMID: 14339937
  25. CHROMOSOMAL ABERRATIONS ASSOCIATED WITH MUTATIONS TO BACTERIOPHAGE RESISTANCE IN ESCHERICHIA COLI.
    J Bacteriol. 1965 Jan;89:28-40 PMID: 14255678
  26. Genetic mapping of the phoR regulator gene of alkaline phosphatase in Escherichia coli.
    J Gen Microbiol. 1969 Nov;59(1):77-81 PMID: 4903904
  27. ON THE TRANSCRIPTION OF THE TRYTOPHAN OPERON IN ESCHERICHIA COLI. I. THE TRYPTOPHAN OPERATOR.
    J Mol Biol. 1965 Jan;11:54-63 PMID: 14255760
  28. Kinetics of transcription and tranalation of a repressed gene.
    J Mol Biol. 1968 Apr 28;33(2):527-31 PMID: 4882736
  29. F-prime factors of Salmonella typhimurium and an inversion between S. typhimurium and Escherichia coli.
    Genetics. 1970 Feb;64(2):215-28 PMID: 4919137
  30. Isolation and characterization of complementation products of Escherichia coli alkaline phosphatase.
    J Mol Biol. 1966 Jan;15(1):32-48 PMID: 5330221
  31. On the transcription of the tryptophan operon in Escherichia coli. 3. Multicistronic messenger RNA and polarity for transcription.
    J Mol Biol. 1965 Aug;13(1):169-82 PMID: 5323613
  32. Orientation of transcription for the amber suppressor gene su 3 as determined by hybridization between tyrosine tRNA and the separated DNA strands of transducing coliphage phi80d su3.
    J Mol Biol. 1969 Jan 14;39(1):239-43 PMID: 4938816
  33. Suppression of mutations in the alkaline phosphatase structural cistron of E. coli.
    Proc Natl Acad Sci U S A. 1962 Jul 15;48:1121-7 PMID: 13896933
  34. Reactivation of arginine genes under the influence of polar mutations.
    FEBS Lett. 1969 Apr;3(1):18-20 PMID: 11946957
  35. Fragments of alkaline phosphatase from nonsense mutants. I. Isolation and characterization of fragments from amber and ochre mutants.
    J Mol Biol. 1969 Nov 14;45(3):549-66 PMID: 4917369
  36. Transposition of the Lac region of E. coli.
    Cold Spring Harb Symp Quant Biol. 1966;31:393-401 PMID: 4866389
  37. New controlling element in the Lac operon of E. coli.
    Nature. 1968 Mar 2;217(5131):825-7 PMID: 4867974
  38. A map of four genes specifying enzymes involved in catabolism of nucleosides and deoxynucleosides in Escherichia coli.
    Mol Gen Genet. 1969 Aug 15;104(4):351-9 PMID: 4904508
  39. Orientation of transcription for the galactose operon as determined by hybridization of gal mRNA with the separated DNA strands of coliphages lambda-dg.
    J Mol Biol. 1968 Jul 14;35(1):207-13 PMID: 4939778
  40. Arabinose-leucine deletion mutants of Escherichia coli B-r.
    J Bacteriol. 1969 Jun;98(3):1159-69 PMID: 4892369
  41. A proposal for a uniform nomenclature in bacterial genetics.
    Genetics. 1966 Jul;54(1):61-76 PMID: 5961488
  42. STUDIES ON THE REGULATION OF TRYPTOPHAN BIOSYNTHESIS IN ESCHERICHIA COLI.
    J Mol Biol. 1965 Apr;11:747-59 PMID: 14338784
  43. Complementation in vivo between structural mutants of alkaline phosphatase from E. coli.
    J Mol Biol. 1963 Jul;7:13-22 PMID: 13946564
  44. REGULATORY MECHANISMS FOR SYNTHESIS OF CAPSULAR POLYSACCHARIDE IN MUCOID MUTANTS OF ESCHERICHIA COLI K12.
    Proc Natl Acad Sci U S A. 1964 Feb;51:239-46 PMID: 14124321
  45. ON THE TRANSLATION OF THE A GENE REGION OF TRYPTOPHAN MESSENGER RNA.
    J Mol Biol. 1964 Apr;8:616-9 PMID: 14153534
  46. Studies with alpha-ketoglutarate dehydrogenase mutants of Escherichia coli.
    Mol Gen Genet. 1969 Oct 13;105(2):182-90 PMID: 4904515
  47. Fingerprint analysis of alkaline phosphatase of Escherichia coli K12.
    J Mol Biol. 1963 Apr;6:330-40 PMID: 13975373
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
Published
1971-09-00
Pages
683-9
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC246988
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com